对 GIPR 信号调控的新认识

IF 31 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM Nature Reviews Endocrinology Pub Date : 2024-08-22 DOI:10.1038/s41574-024-01027-2
Yusman Manchanda, Alejandra Tomas
{"title":"对 GIPR 信号调控的新认识","authors":"Yusman Manchanda, Alejandra Tomas","doi":"10.1038/s41574-024-01027-2","DOIUrl":null,"url":null,"abstract":"Two recent studies have unravelled novel modes of glucose-dependent insulinotropic polypeptide receptor (GIPR) signalling regulation. Kizilkaya et al. characterized the effect of changes in β-arrestin 2 coupling with naturally occurring GIPR coding variants, whereas Regmi et al. investigated GIPR expression profiles and functional regulation in adipocytes.","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"20 10","pages":"571-572"},"PeriodicalIF":31.0000,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"New insights into the regulation of GIPR signalling\",\"authors\":\"Yusman Manchanda, Alejandra Tomas\",\"doi\":\"10.1038/s41574-024-01027-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Two recent studies have unravelled novel modes of glucose-dependent insulinotropic polypeptide receptor (GIPR) signalling regulation. Kizilkaya et al. characterized the effect of changes in β-arrestin 2 coupling with naturally occurring GIPR coding variants, whereas Regmi et al. investigated GIPR expression profiles and functional regulation in adipocytes.\",\"PeriodicalId\":18916,\"journal\":{\"name\":\"Nature Reviews Endocrinology\",\"volume\":\"20 10\",\"pages\":\"571-572\"},\"PeriodicalIF\":31.0000,\"publicationDate\":\"2024-08-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature Reviews Endocrinology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.nature.com/articles/s41574-024-01027-2\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Endocrinology","FirstCategoryId":"3","ListUrlMain":"https://www.nature.com/articles/s41574-024-01027-2","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0

摘要

最近的两项研究揭示了葡萄糖依赖性促胰岛素多肽受体（GIPR）信号调节的新模式。Kizilkaya 等人研究了 β-arrestin 2 与天然 GIPR 编码变体耦合变化的影响，而 Regmi 等人则研究了脂肪细胞中 GIPR 的表达谱和功能调节。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
New insights into the regulation of GIPR signalling
Two recent studies have unravelled novel modes of glucose-dependent insulinotropic polypeptide receptor (GIPR) signalling regulation. Kizilkaya et al. characterized the effect of changes in β-arrestin 2 coupling with naturally occurring GIPR coding variants, whereas Regmi et al. investigated GIPR expression profiles and functional regulation in adipocytes.
求助全文
通过发布文献求助，成功后即可免费获取论文全文。 去求助
来源期刊
Nature Reviews Endocrinology
Nature Reviews Endocrinology 医学-内分泌学与代谢
CiteScore
42.00
自引率
0.70%
发文量
158
审稿时长
6-12 weeks
期刊介绍： Nature Reviews Endocrinology aspires to be the foremost platform for reviews and commentaries catering to the scientific communities it serves. The journal aims to publish articles characterized by authority, accessibility, and clarity, enhanced with easily understandable figures, tables, and other visual aids. The goal is to offer an unparalleled service to authors, referees, and readers, striving to maximize the usefulness and impact of each article. Nature Reviews Endocrinology publishes Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives relevant to researchers and clinicians in the fields of endocrinology and metabolism. Its broad scope ensures that the work it publishes reaches the widest possible audience.
期刊最新文献
Anti-PIT1 hypophysitis after immune checkpoint inhibitor treatment Obesity induces systemic insulin resistance via endothelium-specific insulin receptor inhibition Bone and muscle crosstalk in ageing and disease Sexual dimorphism in pituitary neuroendocrine tumours Neutrophils might link intestinal damage to retinopathy in type 2 diabetes mellitus
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们：info@booksci.cn
Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1