栓塞治疗肺动脉最后正常分支远端肺动静脉畸形的效果。

Junya Ichiki, Koji Yamasaki, Ryusei Zako, Takeshi Wada, Kanta Kitagawa, Takaki Hirano, Aiko Kugimiya, Shuhei Inoue, Kotaro Yamamoto, Ryosuke Usui, Mitsuhiro Kinoshita, Masayoshi Yamamoto, Hiroshi Kondo
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引用次数: 0

摘要

目的:这项针对肺动静脉畸形患者的回顾性研究旨在评估肺动脉最后一根正常分支起源远端栓塞的疗效:2015年9月至2021年10月期间,共有30名连续的38例未经治疗的肺动静脉畸形患者接受了肺动脉最后一根正常分支起源远端线圈栓塞术。患者(5 名男性,25 名女性)的中位数(四分位数间距)年龄为 59 岁(50-68 岁),供血动脉和供血囊的中位数(四分位数间距)大小分别为 2.9 毫米(2.3-3.8 毫米)和 6.7 毫米(5.4-9.7 毫米)。对技术成功率、持续率和治疗相关并发症进行了评估。技术成功率的定义是线圈栓塞后在供血动脉造影中无法识别引流静脉。通过时间分辨磁共振血管造影评估持续率:结果:所有患者的线圈栓塞均成功(100%)。使用线圈栓塞的 38 例肺动静脉畸形患者在 23 个月(10-45 个月)的中位数(四分位数间距)随访期间均未出现持续病变。无重大并发症报告。36次栓塞治疗中只有4次出现轻微并发症,包括2次(6%)局部疼痛和2次(6%)血痰:结论:在肺动脉最后一根正常分支的远端进行栓塞能有效防止肺动静脉畸形的持续存在。
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Effectiveness of Embolization for Pulmonary Arteriovenous Malformations from Distal of the Last Normal Branch of the Pulmonary Artery.

Purpose: This retrospective study of patients with pulmonary arteriovenous malformations aims to assess the efficacy of embolization distal to the origin of the last normal branch of the pulmonary artery.

Material and methods: A total of 30 consecutive patients with 38 untreated pulmonary arteriovenous malformations underwent coil embolization distal to the origin of the last normal branch of the pulmonary artery between September 2015 and October 2021. The median (interquartile range) age of patients (5 males, 25 females) was 59 years (50-68 years old), and the median (interquartile range) sizes of the feeding artery and sac were 2.9 mm (2.3-3.8 mm) and 6.7 mm (5.4-9.7 mm), respectively. The technical success rate, persistence rate, and treatment-related complications were evaluated. Technical success was defined as the inability to identify the draining vein on feeding arteriography after coil embolization. Persistence was assessed using time-resolved magnetic resonance angiography.

Results: Coil embolization was successful in all patients (100%). There was no persistence during a median (interquartile range) follow-up period of 23 months (10-45 months) for the 38 pulmonary arteriovenous malformations embolized with coils. No major complications were reported. Only minor complications following embolization occurred in 4 of 36 sessions, including local pain in 2 sessions (6%) and hemosputum in 2 sessions (6%).

Conclusions: Embolization distal to the origin of the last normal branch of the pulmonary artery is effective in preventing the persistence of pulmonary arteriovenous malformations.

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