深入了解益生菌作为癌症治疗替代药物的作用、机制和应用

Sourik Mukherjee , Dharmender Kumar , Dipanjan Guha
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引用次数: 0

摘要

益生菌是与多种健康益处相关的微生物,通过释放效应分子调节肠道菌群。益生菌在癌症治疗各个阶段的功效已得到充分证明。益生菌可提高癌症免疫疗法的效力,可在治疗前、治疗中或治疗后阶段使用。癌症患者食用益生菌可以最大限度地减少化疗的不利影响,并可作为一种潜在的癌症治疗工具。经过基因工程改造的益生菌可以表达特定的抗原,从而对抗癌症和致命的病原体。益生菌的这些基本特征可用于癌症治疗和其他应用。本综述旨在提供有关益生菌作用机制及其在癌症治疗中应用的最新信息。此外,还讨论了其他一些重要应用,如抗氧化疗法、基于生物技术的改良以及开发有效治疗癌症的强效益生菌株。
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Insights of probiotics as an alternative medicine for cancer therapy, mechanism, and applications

Probiotics are microbes associated with a wide range of health benefits and modulate gut flora by releasing effector molecules. The efficacy of probiotics at various stages of cancer treatment has been well demonstrated. Probiotics can increase the potency of cancer-based immunotherapy, which can be administered before, during, or post-phase therapy. The consumption of probiotics among cancer patients can minimize the detrimental effects of chemotherapy and act as a potential tool for cancer therapy. Genetically engineered probiotics can express specific antigens that can combat cancer and deadly pathogens. These essential features of probiotics can be utilized in cancer treatment and for other applications. This review aims to provide updated information on the mechanism of action of probiotics and their applications in cancer therapy. Moreover, a few other significant applications like; antioxidative therapy, biotechnology-based improvement, and developing potent probiotic strains for effective cancer treatment are also discussed.

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来源期刊
Medicine in Microecology
Medicine in Microecology Medicine-Gastroenterology
CiteScore
5.60
自引率
0.00%
发文量
16
审稿时长
76 days
期刊最新文献
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