{"title":"DNA 纳米开关可抗癌","authors":"Kun Zhou, Chenxiang Lin","doi":"10.1038/s41565-024-01749-4","DOIUrl":null,"url":null,"abstract":"A DNA origami nanodevice presents its hidden death ligand pattern in the acidic tumour microenvironment to kill cancerous cells, opening opportunities for effective and safe cancer therapy.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"59 1","pages":""},"PeriodicalIF":38.1000,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"DNA nanoswitches pack an anti-cancer punch\",\"authors\":\"Kun Zhou, Chenxiang Lin\",\"doi\":\"10.1038/s41565-024-01749-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A DNA origami nanodevice presents its hidden death ligand pattern in the acidic tumour microenvironment to kill cancerous cells, opening opportunities for effective and safe cancer therapy.\",\"PeriodicalId\":18915,\"journal\":{\"name\":\"Nature nanotechnology\",\"volume\":\"59 1\",\"pages\":\"\"},\"PeriodicalIF\":38.1000,\"publicationDate\":\"2024-08-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature nanotechnology\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.1038/s41565-024-01749-4\",\"RegionNum\":1,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature nanotechnology","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1038/s41565-024-01749-4","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
摘要
一种 DNA 折纸纳米装置在酸性肿瘤微环境中呈现出其隐藏的死亡配体模式，从而杀死癌细胞，为有效、安全的癌症治疗提供了机会。
A DNA origami nanodevice presents its hidden death ligand pattern in the acidic tumour microenvironment to kill cancerous cells, opening opportunities for effective and safe cancer therapy.
期刊介绍：
Nature Nanotechnology is a prestigious journal that publishes high-quality papers in various areas of nanoscience and nanotechnology. The journal focuses on the design, characterization, and production of structures, devices, and systems that manipulate and control materials at atomic, molecular, and macromolecular scales. It encompasses both bottom-up and top-down approaches, as well as their combinations.
Furthermore, Nature Nanotechnology fosters the exchange of ideas among researchers from diverse disciplines such as chemistry, physics, material science, biomedical research, engineering, and more. It promotes collaboration at the forefront of this multidisciplinary field. The journal covers a wide range of topics, from fundamental research in physics, chemistry, and biology, including computational work and simulations, to the development of innovative devices and technologies for various industrial sectors such as information technology, medicine, manufacturing, high-performance materials, energy, and environmental technologies. It includes coverage of organic, inorganic, and hybrid materials.
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