极快的高分辨率聚合 3D 检测 CAM,可快速准确地找到面部骨折区域

IF 4.9 2区 医学 Q1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Computer methods and programs in biomedicine Pub Date : 2024-08-19 DOI:10.1016/j.cmpb.2024.108379
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引用次数: 0

摘要

背景和目的:面部骨折的发病率在全球范围内呈上升趋势,但针对面部骨折在三维图像中的不同表现形式的研究却十分有限。特别是,由于面部骨折的性质、骨折方向的不同以及没有清晰的轮廓,很难在二维图像中确定骨折的确切位置。因此,需要通过三维图像分析来找到准确的骨折区域,但这需要很高的计算复杂度和昂贵的像素标注监督学习。在本研究中,我们通过在三维图像空间中使用弱监督对象定位(无需像素标注)来解决减轻计算负担和提高骨折定位准确性的问题。方法:我们提出了一种快速、高分辨率聚合三维检测 CAM(VFHA-CAM)模型,它可以检测各种面部骨折。为了更好地检测微小骨折,我们的模型使用了高分辨率特征图,并采用了消融 CAM 技术,在不进行像素标注的情况下找到准确的骨折位置。结果:实验结果表明,VFHA-CAM 在灵敏度/人和特异度/人方面比最先进的二维检测方法高出 20%,灵敏度/人和特异度/人得分分别达到 87% 和 85%。此外,与耗时超过 20 分钟的简单消融 CAM 方法相比,我们的 VFHA-CAM 将定位分析时间缩短到 76 秒,而性能却没有下降。该方法采用三维检测模型,有助于准确检测各种形式的面部骨折。在三维骨折检测框内采用 CAM 算法进行骨折区域分割,是在弱监督对象定位中快速告知医务人员面部骨折确切位置的关键。此外,我们还提供了三维可视化功能,即使是不熟悉三维 CT 图像的非专业人员也能识别骨折状态和位置。
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Very fast, high-resolution aggregation 3D detection CAM to quickly and accurately find facial fracture areas

Background and objective:

The incidence of facial fractures is on the rise globally, yet limited studies are addressing the diverse forms of facial fractures present in 3D images. In particular, due to the nature of the facial fracture, the direction in which the bone fractures vary, and there is no clear outline, it is difficult to determine the exact location of the fracture in 2D images. Thus, 3D image analysis is required to find the exact fracture area, but it needs heavy computational complexity and expensive pixel-wise labeling for supervised learning. In this study, we tackle the problem of reducing the computational burden and increasing the accuracy of fracture localization by using a weakly-supervised object localization without pixel-wise labeling in a 3D image space.

Methods:

We propose a Very Fast, High-Resolution Aggregation 3D Detection CAM (VFHA-CAM) model, which can detect various facial fractures. To better detect tiny fractures, our model uses high-resolution feature maps and employs Ablation CAM to find an exact fracture location without pixel-wise labeling, where we use a rough fracture image detected with 3D box-wise labeling. To this end, we extract important features and use only essential features to reduce the computational complexity in 3D image space.

Results:

Experimental findings demonstrate that VFHA-CAM surpasses state-of-the-art 2D detection methods by up to 20% in sensitivity/person and specificity/person, achieving sensitivity/person and specificity/person scores of 87% and 85%, respectively. In addition, Our VFHA-CAM reduces location analysis time to 76 s without performance degradation compared to a simple Ablation CAM method that takes more than 20 min.

Conclusion:

This study introduces a novel weakly-supervised object localization approach for bone fracture detection in 3D facial images. The proposed method employs a 3D detection model, which helps detect various forms of facial bone fractures accurately. The CAM algorithm adopted for fracture area segmentation within a 3D fracture detection box is key in quickly informing medical staff of the exact location of a facial bone fracture in a weakly-supervised object localization. In addition, we provide 3D visualization so that even non-experts unfamiliar with 3D CT images can identify the fracture status and location.

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来源期刊
Computer methods and programs in biomedicine
Computer methods and programs in biomedicine 工程技术-工程:生物医学
CiteScore
12.30
自引率
6.60%
发文量
601
审稿时长
135 days
期刊介绍: To encourage the development of formal computing methods, and their application in biomedical research and medical practice, by illustration of fundamental principles in biomedical informatics research; to stimulate basic research into application software design; to report the state of research of biomedical information processing projects; to report new computer methodologies applied in biomedical areas; the eventual distribution of demonstrable software to avoid duplication of effort; to provide a forum for discussion and improvement of existing software; to optimize contact between national organizations and regional user groups by promoting an international exchange of information on formal methods, standards and software in biomedicine. Computer Methods and Programs in Biomedicine covers computing methodology and software systems derived from computing science for implementation in all aspects of biomedical research and medical practice. It is designed to serve: biochemists; biologists; geneticists; immunologists; neuroscientists; pharmacologists; toxicologists; clinicians; epidemiologists; psychiatrists; psychologists; cardiologists; chemists; (radio)physicists; computer scientists; programmers and systems analysts; biomedical, clinical, electrical and other engineers; teachers of medical informatics and users of educational software.
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