牙周管理可减少老年人因急性冠状动脉综合征和中风而住院的人数

Ayako Edahiro , Tatsuro Ishizaki , Seigo Mitsutake , Akihiko Kitamura , Takumi Hirata , Atsushi Saito
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引用次数: 0

摘要

背景本研究旨在通过对日本健康保险理赔数据的回顾性分析,研究牙周管理对急性冠状动脉综合征和中风发生率的影响。方法分析包括2016年9月至2017年2月期间被诊断患有牙周病并接受治疗的年龄≥75岁的个人的健康保险理赔数据。在2017年3月至2019年3月的随访期间,观察了与急性冠状动脉综合征和中风相关的住院治疗作为结果事件。使用广义线性混合模型对性别、年龄、居住地和慢性病等协变量进行了调整。结果该研究涉及 117010 名参与者,平均年龄为(80.0 ± 4.0)岁,男性占 44.7%。分析表明,支持性牙周治疗可显著降低急性冠状动脉综合征的住院风险(调整赔率比:AOR 0.88,P = 0.017)。结论牙周治疗与急性住院风险的降低有关。定期进行牙周治疗,以减少口腔慢性炎症,有可能降低急性冠状动脉综合征和中风的发病风险。
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Periodontal management may reduce hospitalization for acute coronary syndrome and stroke in older individuals

Background

This study aimed to examine the impact of periodontal management on the occurrence of acute coronary syndrome and stroke using retrospective analysis of Japanese health insurance claims data.

Methods

The analysis included health insurance claims data of individuals aged ≥ 75 years who had been diagnosed with periodontal disease and received treatment between September 2016 and February 2017. Hospitalizations related to acute coronary syndrome and stroke were observed as outcome events during the follow-up period from March 2017 to March 2019. Covariates such as sex, age, place of residence, and chronic diseases were adjusted for using a generalized linear mixed model.

Results

The study involved 117,010 participants with a mean age of 80.0 ± 4.0 years, and 44.7 % were male. The analysis suggested that supportive periodontal therapy significantly reduced the risk of hospitalization for acute coronary syndrome (adjusted odds ratio: AOR 0.88, P = 0.017). Supportive periodontal therapy also showed a borderline significant 13 % reduction in stroke hospitalizations.

Conclusions

Periodontal treatment is associated with a decreased risk of acute hospitalization. Regular periodontal management, aimed at minimizing oral chronic inflammation, can potentially lower the risk of developing acute coronary syndrome and stroke.

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