日本痴呆症患者在 COVID-19 前后 ADL 下降的因素

Taiga Fuju , Natsumi Shinya , Kumiko Yamada , Reiko Oshima , Taiki Yoshita , Naoya Tsukii , Yuta Ishimitsu , Naoto Okonogi , Yukiko Tanaka , Tomoyuki Shinohara
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摘要

背景本研究旨在调查2019年冠状病毒病(COVID-19)爆发后痴呆症患者日常生活活动能力(ADL)下降的决定因素。研究队列在COVID-19疫情爆发后再次入院,时间跨度为2022年9月至12月。研究采用了多变量广义线性混合效应模型来评估再入院时的巴特尔指数,并将其作为因变量。如果签约 COVID-19 之前的人口统计学变量与再入院时的 Barthel 指数显著相关,则将其视为独立预测变量。结果护理水平、失能老年人独立生活的程度以及进行日常活动的能力与再入院时的 Barthel 指数显著相关。如果将日常活动能力(贝塔值=0.350)和护理水平(贝塔值=-0.347)作为自变量,它们与再入院时的巴特尔指数有明显的相关性。结论 日常活动能力会影响 COVID-19 导致的 ADLs 下降。
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Factors for the decline of ADL before and after the COVID-19 of people with dementia in Japan

Background

This study aimed to investigate the determinants of decline in activities of daily living (ADL) among people with dementia following the onset of the coronavirus disease of 2019 (COVID-19).

Methods

A retrospective analysis was performed, including 37 individuals with dementia residing in group and nursing homes. The study cohort experienced a resurgence in facility admissions following COVID-19 outbreak, spanning from September to December 2022. Multivariate generalized linear mixed-effects models were employed to assess the Barthel Index at the time of readmission, which served as the dependent variable. Demographic variables before contracting COVID-19 were considered independent predictors if they were significantly associated with the Barthel Index at the time of readmission. Random intercepts were applied to account for variations among facilities in which individuals resided before contracting COVID-19.

Results

Care level, degree of independent living for disabled older adults, and the ability to perform daily ambulatory movements were significantly associated with the Barthel Index at the time of readmission. When used as independent variables, both daily ambulatory movement (beta = 0.350) and care level (beta = -0.347) showed significant associations with the Barthel Index at the time of readmission. Whereas using daily ambulatory movements and the degree of independent living for disabled older adults as independent variables, only the degree of independent living for disabled older adults (beta = -0.757) was significantly associated with the Barthel Index at the time of readmission.

Conclusion

The ability to engage in daily ambulatory movement affects the decline in ADLs due to COVID-19.

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