Letícia Florindo Pereira, Lucas José de Azevedo-Silva, Pedro Rodrigues Minim, Paulo Noronha Lisboa-Filho, Carlos Alberto Fortulan, Jason Alan Griggs, Brunna Mota Ferrairo, Ana Flávia Sanches Borges
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Three experimental groups were developed (HA, HA+5 %TiO<sub>2</sub> and HA+8 %TiO<sub>2</sub>) and subjected to X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), indentation fracture (IF), biaxial flexural strength (BFS) and chemical solubility test.</p><p><strong>Results: </strong>XRD revealed, for HA group, the appearance of a peak corresponding to b-tricalcium phosphate (ß-TCP). For HA+ 5 %TiO<sub>2</sub> and HA+ 8 %TiO<sub>2,</sub> the entire composition was converted into ß-TCP and calcium titanate (CaTiO<sub>3</sub>). The SEM images showed a dense ceramic matrix and a uniform distribution of another phase in groups with TiO<sub>2</sub> nanoparticles. HA+ 5 %TiO<sub>2</sub> (1.40 ± 0.18 MPa.m<sup>1/2</sup>) and HA+ 8 %TiO<sub>2</sub> (1.32 ± 0.18 MPa.m<sup>1/2</sup>) showed significantly higher fracture toughness values than HA (0.67 ± 0.09 MPa.m<sup>1/2</sup>). HA showed significantly higher characteristic stress (295.8 MPa) in comparison to groups with 5 % (235.1 MPa) and 8 % (214.4 MPa) TiO<sub>2</sub> nanoparticles. Differences were not observed between the Weibull modulus values. The solubility results indicated that all experimental ceramics were above the 2000 ug/cm<sup>2</sup> limit set by the ISO 6872:2015.</p><p><strong>Significance: </strong>This study proposed the development and characterization of a new ceramic for dental prosthesis made from HA extracted from bovine bones, with the intention of reusing these solids waste and transforming them into a sustainable and low-cost material. Although the experimental calcium phosphate ceramic with additions of 5 % and 8 % of TiO<sub>2</sub> achieved desirable mechanical properties, the chemical solubility values were very high.</p>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Are we approaching the development of a novel calcium phosphate-based bioceramic dental material?\",\"authors\":\"Letícia Florindo Pereira, Lucas José de Azevedo-Silva, Pedro Rodrigues Minim, Paulo Noronha Lisboa-Filho, Carlos Alberto Fortulan, Jason Alan Griggs, Brunna Mota Ferrairo, Ana Flávia Sanches Borges\",\"doi\":\"10.1016/j.dental.2024.07.019\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>Develop a sustainable bovine hydroxyapatite dental ceramic with the addition of titanium dioxide (TiO<sub>2</sub>) nanoparticles (5 % and 8 % by weight), analyzing the outcome of this addition to the microstructure, as well as its mechanical and chemical properties, in order to evaluate whether they satisfy the International Organization for Standardization (ISO) 6872:2015 for dental ceramics or not.</p><p><strong>Methods: </strong>Disks were obtained through uniaxial followed by isostatic pressing from bovine hydroxyapatite powder and TiO<sub>2</sub> nanoparticles and sintered at 1300ºC for 2 h. Three experimental groups were developed (HA, HA+5 %TiO<sub>2</sub> and HA+8 %TiO<sub>2</sub>) and subjected to X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), indentation fracture (IF), biaxial flexural strength (BFS) and chemical solubility test.</p><p><strong>Results: </strong>XRD revealed, for HA group, the appearance of a peak corresponding to b-tricalcium phosphate (ß-TCP). For HA+ 5 %TiO<sub>2</sub> and HA+ 8 %TiO<sub>2,</sub> the entire composition was converted into ß-TCP and calcium titanate (CaTiO<sub>3</sub>). The SEM images showed a dense ceramic matrix and a uniform distribution of another phase in groups with TiO<sub>2</sub> nanoparticles. HA+ 5 %TiO<sub>2</sub> (1.40 ± 0.18 MPa.m<sup>1/2</sup>) and HA+ 8 %TiO<sub>2</sub> (1.32 ± 0.18 MPa.m<sup>1/2</sup>) showed significantly higher fracture toughness values than HA (0.67 ± 0.09 MPa.m<sup>1/2</sup>). 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Are we approaching the development of a novel calcium phosphate-based bioceramic dental material?
Objectives: Develop a sustainable bovine hydroxyapatite dental ceramic with the addition of titanium dioxide (TiO2) nanoparticles (5 % and 8 % by weight), analyzing the outcome of this addition to the microstructure, as well as its mechanical and chemical properties, in order to evaluate whether they satisfy the International Organization for Standardization (ISO) 6872:2015 for dental ceramics or not.
Methods: Disks were obtained through uniaxial followed by isostatic pressing from bovine hydroxyapatite powder and TiO2 nanoparticles and sintered at 1300ºC for 2 h. Three experimental groups were developed (HA, HA+5 %TiO2 and HA+8 %TiO2) and subjected to X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), indentation fracture (IF), biaxial flexural strength (BFS) and chemical solubility test.
Results: XRD revealed, for HA group, the appearance of a peak corresponding to b-tricalcium phosphate (ß-TCP). For HA+ 5 %TiO2 and HA+ 8 %TiO2, the entire composition was converted into ß-TCP and calcium titanate (CaTiO3). The SEM images showed a dense ceramic matrix and a uniform distribution of another phase in groups with TiO2 nanoparticles. HA+ 5 %TiO2 (1.40 ± 0.18 MPa.m1/2) and HA+ 8 %TiO2 (1.32 ± 0.18 MPa.m1/2) showed significantly higher fracture toughness values than HA (0.67 ± 0.09 MPa.m1/2). HA showed significantly higher characteristic stress (295.8 MPa) in comparison to groups with 5 % (235.1 MPa) and 8 % (214.4 MPa) TiO2 nanoparticles. Differences were not observed between the Weibull modulus values. The solubility results indicated that all experimental ceramics were above the 2000 ug/cm2 limit set by the ISO 6872:2015.
Significance: This study proposed the development and characterization of a new ceramic for dental prosthesis made from HA extracted from bovine bones, with the intention of reusing these solids waste and transforming them into a sustainable and low-cost material. Although the experimental calcium phosphate ceramic with additions of 5 % and 8 % of TiO2 achieved desirable mechanical properties, the chemical solubility values were very high.
期刊介绍：
Dental Materials publishes original research, review articles, and short communications.
Academy of Dental Materials members click here to register for free access to Dental Materials online.
The principal aim of Dental Materials is to promote rapid communication of scientific information between academia, industry, and the dental practitioner. Original Manuscripts on clinical and laboratory research of basic and applied character which focus on the properties or performance of dental materials or the reaction of host tissues to materials are given priority publication. Other acceptable topics include application technology in clinical dentistry and dental laboratory technology.
Comprehensive reviews and editorial commentaries on pertinent subjects will be considered.
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