内镜反应可降低克罗恩病样袋炎症患者继发袋炎的风险

IF 8 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY American Journal of Gastroenterology Pub Date : 2025-01-01 Epub Date: 2024-08-27 DOI:10.14309/ajg.0000000000003055

Maia Kayal, Hannah Posner, Darwin Jimenez, Justin Huang, Marla C Dubinsky, Jean Frederic Colombel

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引用次数: 0

摘要

导言：本研究旨在报告正在接受治疗的克罗恩病样储袋炎症（CDLPI）患者出现内镜反应和缓解的频率及其对后续储袋炎风险的影响：这是一项针对18岁以上正在接受治疗的CDLPI患者的单中心回顾性研究：结果：在110名临床缓解的CDLPI患者中，内镜缓解与内镜反应相比，并不明显降低随后发生袋炎的风险：结论：内镜反应（而非缓解）足以降低 CDLPI 患者罹患后续储袋炎的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Endoscopic Response Reduces the Risk of Subsequent Pouchitis in Patients With Crohn's Disease-Like Pouch Inflammation.

Introduction: The aim of this study was to report the frequency and impact of endoscopic response and remission on the risk of subsequent pouchitis in patients with Crohn's disease-like pouch inflammation (CDLPI) on therapy.

Methods: This was a single-center retrospective study of patients older than 18 years with CDLPI on therapy.

Results: Among 110 included patients with CDLPI in clinical remission, endoscopic remission was not significantly associated with a reduced risk of subsequent pouchitis when compared with endoscopic response.

Discussion: Endoscopic response, not remission, is sufficient to reduce the risk of subsequent pouchitis in patients with CDLPI.

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来源期刊

American Journal of Gastroenterology 医学-胃肠肝病学

CiteScore

11.40

自引率

5.10%

发文量

458

审稿时长

12 months

期刊介绍： Published on behalf of the American College of Gastroenterology (ACG), The American Journal of Gastroenterology (AJG) stands as the foremost clinical journal in the fields of gastroenterology and hepatology. AJG offers practical and professional support to clinicians addressing the most prevalent gastroenterological disorders in patients.