用于检测食源性霉菌毒素的生物传感器的进展。

IF 4.2 2区 化学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Molecules Pub Date : 2024-08-22 DOI:10.3390/molecules29163974
Yangyang Li, Dan Zhang, Xiaoyuan Zeng, Cheng Liu, Yan Wu, Cuicui Fu
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引用次数: 0

摘要

食源性霉菌毒素(FBMTs)是由食物本身或在加工和运输过程中产生的毒素,对公共卫生安全构成巨大威胁。然而,传统的仪器和化学方法检测毒素存在操作难度大、耗时长、成本高等缺点,限制了其大规模应用。近年来,基于适配体的生物传感器因其亲和力强、特异性好、响应速度快等特点,已成为食品安全风险评估和监测的新工具。在这篇综述中,我们重点介绍了近年来单模和双模适配体在基础研究和设备应用方面取得的进展。此外,我们还指出了当前检测策略中存在的一些问题,旨在激励未来的毒素检测系统向操作简便、检测快速的方向过渡。
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Advances in Aptamer-Based Biosensors for the Detection of Foodborne Mycotoxins.

Foodborne mycotoxins (FBMTs) are toxins produced by food itself or during processing and transportation that pose an enormous threat to public health security. However, traditional instrumental and chemical methods for detecting toxins have shortcomings, such as high operational difficulty, time consumption, and high cost, that limit their large-scale applications. In recent years, aptamer-based biosensors have become a new tool for food safety risk assessment and monitoring due to their high affinity, good specificity, and fast response. In this review, we focus on the progress of single-mode and dual-mode aptasensors in basic research and device applications over recent years. Furthermore, we also point out some problems in the current detection strategies, with the aim of stimulating future toxin detection systems for a transition toward ease of operation and rapid detection.

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来源期刊
Molecules
Molecules 化学-有机化学
CiteScore
7.40
自引率
8.70%
发文量
7524
审稿时长
1.4 months
期刊介绍: Molecules (ISSN 1420-3049, CODEN: MOLEFW) is an open access journal of synthetic organic chemistry and natural product chemistry. All articles are peer-reviewed and published continously upon acceptance. Molecules is published by MDPI, Basel, Switzerland. Our aim is to encourage chemists to publish as much as possible their experimental detail, particularly synthetic procedures and characterization information. There is no restriction on the length of the experimental section. In addition, availability of compound samples is published and considered as important information. Authors are encouraged to register or deposit their chemical samples through the non-profit international organization Molecular Diversity Preservation International (MDPI). Molecules has been launched in 1996 to preserve and exploit molecular diversity of both, chemical information and chemical substances.
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