洗耳对犬外耳道炎治疗效果的影响

IF 1.9 3区 农林科学 Q3 DERMATOLOGY Veterinary dermatology Pub Date : 2024-12-01 Epub Date: 2024-08-30 DOI:10.1111/vde.13292
Erin Corb, Craig E Griffin, Willie Bidot, Melissa Hall, Allison Kirby, Wayne Rosenkrantz
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引用次数: 0

摘要

背景:在犬外耳道炎(OE)的治疗中,通常建议进行耳部清洁。很少有体内研究评估耳朵清洁如何影响治疗效果:通过比较已清洁耳朵与未清洁耳朵的治疗效果,确定清洁耳朵对犬外耳道炎的影响:23只客户饲养的患有耵聍性或化脓性OE的犬:40只耳朵被随机分为两组:20只耳朵用干纱布或生理盐水浸湿的纱布擦拭(grp1),20只外耳道用商业产品进行人工清洁(grp2)。每隔 24 小时在患耳上涂抹一毫升含有醋酸氢化可的松、硝酸咪康唑和硫酸庆大霉素的商用耳悬液,持续五天。比较第 0 天和第 7 天的细胞学评分、改良耳炎指数评分(OTIS3)、瘙痒视觉模拟量表(PVAS)、改良 PVAS 和客户问卷:第 7 天时,各组的细胞学评分、改良的 OTIS3、PVAS、改良的 PVAS 或客户评估之间均无统计学差异。从第 0 天到第 7 天,两组的所有治疗参数都有明显降低,但细胞学杆状评分除外,只有清洁耳的细胞学杆状评分有明显降低。结论和临床意义:无论清洁与否,两组患者都取得了成功。当存在杆状细菌时,耳部清洁可能更为重要。
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Effect of ear cleaning on treatment outcome for canine otitis externa.

Background: Ear cleaning is often recommended for management of canine otitis externa (OE). Few in vivo studies evaluate how ear cleaning affects treatment outcome.

Hypothesis/objectives: To determine the effect of ear cleaning on canine OE by comparing treatment outcome in cleaned versus noncleaned ears.

Animals: Twenty-three client-owned dogs with ceruminous or purulent OE.

Materials and methods: Forty ears were randomised to one of two groups: 20 ears were wiped with dry or saline-moistened gauze (grp1), and 20 external ear canals received manual cleaning (grp2) with a commercial product. One millilitre of a commercial otic suspension containing hydrocortisone aceponate, miconazole nitrate and gentamicin sulfate was applied to affected ears every 24 h for five days. Cytological scores, modified otitis index score (OTIS3), pruritus Visual Analog Scale (PVAS), modified PVAS and client questionnaire were compared on Day (D)0 and D7.

Results: There were no statistical differences between cytological scores, modified OTIS3, PVAS, modified PVAS or client assessments between groups at D7. Both groups had significant reduction in all treatment parameters from D0 to D7 with the exception of cytological rod scores that were only significantly decreased in cleaned ears. There was a significant difference in OTIS3 before and after cleaning on D0.

Conclusions and clinical relevance: Both groups achieved successful outcome regardless of cleaning. Ear cleaning may be more important when rod-shaped bacteria are present.

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来源期刊
Veterinary dermatology
Veterinary dermatology 农林科学-兽医学
CiteScore
3.20
自引率
21.40%
发文量
92
审稿时长
12-24 weeks
期刊介绍: Veterinary Dermatology is a bi-monthly, peer-reviewed, international journal which publishes papers on all aspects of the skin of mammals, birds, reptiles, amphibians and fish. Scientific research papers, clinical case reports and reviews covering the following aspects of dermatology will be considered for publication: -Skin structure (anatomy, histology, ultrastructure) -Skin function (physiology, biochemistry, pharmacology, immunology, genetics) -Skin microbiology and parasitology -Dermatopathology -Pathogenesis, diagnosis and treatment of skin diseases -New disease entities
期刊最新文献
Long-lasting otic solution containing mometasone furoate can influence intradermal testing in dogs with healthy ears and otitis externa. Clinical features, surgical management and outcome of squamous and basal cell carcinoma in squamates and chelonians. Skin barrier, phenotypic and genotypic characterisation of autosomal recessive ichthyosis in TGM1-deficient Jack Russell Terriers and response to topical ceramide. Treatment of moderate-to-severe canine atopic dermatitis with modified-release mycophenolate (OKV-1001): A pilot open-label, single-arm multicentric clinical trial. Analysis of the immunomodulatory properties of mycobacterium cell wall fraction on the cytokine production of peripheral blood mononuclear cells of healthy dogs.
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