应用和评估早期子宫内膜癌的微创手术治疗方案。

IF 1.4 4区 医学 Q4 ENGINEERING, BIOMEDICAL Technology and Health Care Pub Date : 2024-08-01 DOI:10.3233/THC-240439
Leilei Xu, Fu Hua, Changhua Li, Tong Xu
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引用次数: 0

摘要

背景:腹腔镜和机器人辅助技术越来越受欢迎,而子宫内膜癌(EC)仍然是妇女健康的一个重要问题:本文旨在评估早期子宫内膜癌微创手术(MIS)治疗方案的有效性和安全性。我们还调查了微创手术和开放手术(OS)对早期子宫内膜癌患者的肿瘤治疗效果的差异。患者被诊断为早期EC并接受腹腔镜手术治疗,是回顾性分析的重点。分析了162名早期EC患者,诊断时间为2002年至2022年:将患者分为两组,一组接受手术治疗,另一组接受腹腔镜手术治疗。两种方法的肿瘤总切除率和复发率相同,表明肿瘤学结果相似。两组的并发症发生率也相当:机器人辅助手术患者的生活质量评分高于腹腔镜手术患者。在这项研究的162名患者中,62人(62.2%)获得了OS,56人(57.8%)获得了MIS。接受OS手术的女性中,EC在III期至IV期复发的概率明显更高:微创手术被证明能有效治疗早期EC,虽然这些研究结果为使用微创手术提供了支持,但还需要更大规模的多中心随机对照研究来验证这些结果,并进一步研究可能的长期优势。无论组织学类型如何,早期EC患者采用微创手术的存活率均优于OS。
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Application and evaluation of minimally invasive surgical treatment options for early endometrial cancer.

Background: Laparoscopic and robotic-assisted techniques have gained popularity, and endometrial cancer (EC) remains a significant health problem among women.

Objective: Minimally invasive surgical (MIS) therapy options for early endometrial cancer will be evaluated for their effectiveness and safety is the aim of this paper. We also investigate the differences in oncologic outcomes between MIS and open surgery (OS) for individuals with early-stage EC. The patient was diagnosed with early-stage EC and treated with laparoscopic surgery and was the focus of a retrospective analysis. 162 patients with early EC were analyzed, with diagnoses occurring between 2002 and 2022.

Methods: The patients were fragmented into two groups, one for OS and another for laparoscopic procedures. The total tumor excision and recurrence rates were identical across the two methods, indicating similar oncologic results. Rates of complications were likewise comparable across the two groups.

Results: The quality of life ratings of patients with robotic-assisted surgery was higher than those with laparoscopic surgery. Sixty-two (62.2%) of the 162 patients in this research had OS, whereas Fifty-six (57.8%) had MIS. The probability of recurrence of EC from stages III to IV was significanitly higher in women who had OS.

Conclusion: Minimally invasive procedures were shown to be effective in treating early-stage EC, and while these findings provide support for their usage, larger multicenter randomized controlled studies are required to verify these results and further examine possible long-term advantages. Patients with early-stage EC, regardless of histologic type, had superior survival rates with MIS compared to OS.

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来源期刊
Technology and Health Care
Technology and Health Care HEALTH CARE SCIENCES & SERVICES-ENGINEERING, BIOMEDICAL
CiteScore
2.10
自引率
6.20%
发文量
282
审稿时长
>12 weeks
期刊介绍: Technology and Health Care is intended to serve as a forum for the presentation of original articles and technical notes, observing rigorous scientific standards. Furthermore, upon invitation, reviews, tutorials, discussion papers and minisymposia are featured. The main focus of THC is related to the overlapping areas of engineering and medicine. The following types of contributions are considered: 1.Original articles: New concepts, procedures and devices associated with the use of technology in medical research and clinical practice are presented to a readership with a widespread background in engineering and/or medicine. In particular, the clinical benefit deriving from the application of engineering methods and devices in clinical medicine should be demonstrated. Typically, full length original contributions have a length of 4000 words, thereby taking duly into account figures and tables. 2.Technical Notes and Short Communications: Technical Notes relate to novel technical developments with relevance for clinical medicine. In Short Communications, clinical applications are shortly described. 3.Both Technical Notes and Short Communications typically have a length of 1500 words. Reviews and Tutorials (upon invitation only): Tutorial and educational articles for persons with a primarily medical background on principles of engineering with particular significance for biomedical applications and vice versa are presented. The Editorial Board is responsible for the selection of topics. 4.Minisymposia (upon invitation only): Under the leadership of a Special Editor, controversial or important issues relating to health care are highlighted and discussed by various authors. 5.Letters to the Editors: Discussions or short statements (not indexed).
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