阈下微脉冲黄色激光治疗急性中心性浆液性脉络膜视网膜病变中两种激光功率水平的比较。

IF 3.1 3区 医学 Q2 ONCOLOGY Photodiagnosis and Photodynamic Therapy Pub Date : 2024-08-29 DOI:10.1016/j.pdpdt.2024.104323
Liru Qin , Daming Li , Yuzhe Zhou , Han Zhang , Guisen Zhang , Xiurong Zhang , Wei Shi
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引用次数: 0

摘要

目的:比较 577 纳米阈下微脉冲激光(SML)治疗急性中心性浆液性脉络膜视网膜病变(aCSC)的两种功率水平的疗效:方法:进行了一项回顾性比较研究。共有 65 名 aCSC 患者(65 只眼)入组。其中,32 名患者接受了低功率治疗,33 名患者接受了 577 纳米 SML 的高功率治疗。在基线和 3 个月时对最佳矫正视力 (BCVA)、黄斑中心厚度 (CMT)、眼底监测显微透视测量、眼底脉络膜厚度高度 (SFCT) 以及视网膜下积液 (SRF) 进行了评估:结果:4周时,低功率治疗组的SFCT高度和视网膜灵敏度明显优于高功率治疗组(P均<0.001)。从基线到治疗后 3 个月,BCVA 平均值有所改善,但 3 个月后两组间无明显差异(P > 0.05)。低功率组的 CMT 从基线时的 379.76 ± 139.23 μm 下降到 3 个月时的 176.56 ± 37.78 μm,而高功率组的 CMT 从基线时的 364.97 ± 143.08 μm 下降到 3 个月时的 191.77 ± 38.26 μm。两组在 3 个月时无明显差异(P > 0.05)。在 SRF 方面也发现了类似的结果:结论:及时使用 577 nm SML 进行低功率治疗可提高视力,并获得解剖学上的成功,且无不良反应。
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Comparison of two laser power levels in the subthreshold micropulse yellow laser treatment of acute central serous chorioretinopathy

Aims

To compare the efficacy of two power levels in the 577 nm sub-threshold micro pulse laser (SML) treatment of acute central serous chorioretinopathy (aCSC).

Methods

A retrospective comparative study was conducted. A total of 65 patients (65 eyes) with aCSC were enrolled. Of which, 32 patients received low power treatment and 33 patients received high power treatment of 577 nm SML. Best-corrected visual acuity (BCVA), central macular thickness (CMT), fundus-monitored microperimetry and height of subfoveal choroidal thickness (SFCT) as well as subretinal fluid (SRF) were evaluated at baseline and 3 months.

Results

The height of SFCT and retinal sensitivity in the low power treatment group was significantly better than that in the high power treatment group at 4 weeks (all p < 0.001). Mean BCVA improved from baseline to 3 months after treatments but with no significant difference between the two groups after 3 months (p > 0.05). In the low power group, the CMT decreased from 379.76 ± 139.23 μm at baseline to 176.56 ± 37.78 μm at 3 months, and in the high power group, the CMT decreased from 364.97 ± 143.08 at baseline to 191.77 ± 38.26 μm at 3 months. There was no significant difference at 3 months between the two groups (p > 0.05). Similar results were also found in term of SRF.

Conclusions

Timely intervention with 577 nm SML with low power treatment can improve visual acuity, and included anatomic success without adverse events.

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来源期刊
CiteScore
5.80
自引率
24.20%
发文量
509
审稿时长
50 days
期刊介绍: Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.
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