利用新一代测序技术确定新型 HLA-DQB1*05:305 等位基因的特征。

IF 5.9 4区 医学 Q2 CELL BIOLOGY HLA Pub Date : 2024-09-03 DOI:10.1111/tan.15667
Nanying Chen, Yizhen He, Lina Dong, Wei Zhang, Faming Zhu
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引用次数: 0

摘要

与 HLA-DQB1*05:03:01:01 相比,HLA-DQB1*05:305 在 664 位有一个单核苷酸替换。
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Characterisation of the novel HLA-DQB1*05:305 allele using next-generation sequencing

HLA-DQB1*05:305 shows one single nucleotide substitution at position 664 compared with HLA-DQB1*05:03:01:01.

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来源期刊
HLA
HLA Immunology and Microbiology-Immunology
CiteScore
3.00
自引率
28.80%
发文量
368
期刊介绍: HLA, the journal, publishes articles on various aspects of immunogenetics. These include the immunogenetics of cell surface antigens, the ontogeny and phylogeny of the immune system, the immunogenetics of cell interactions, the functional aspects of cell surface molecules and their natural ligands, and the role of tissue antigens in immune reactions. Additionally, the journal covers experimental and clinical transplantation, the relationships between normal tissue antigens and tumor-associated antigens, the genetic control of immune response and disease susceptibility, and the biochemistry and molecular biology of alloantigens and leukocyte differentiation. Manuscripts on molecules expressed on lymphoid cells, myeloid cells, platelets, and non-lineage-restricted antigens are welcomed. Lastly, the journal focuses on the immunogenetics of histocompatibility antigens in both humans and experimental animals, including their tissue distribution, regulation, and expression in normal and malignant cells, as well as the use of antigens as markers for disease.
期刊最新文献
HLA-DQA1*05:115, the first DQA1 allele described with an alanine at position 59 of alpha-1 domain Identification of the novel HLA-C*08:291 allele by next-generation sequencing A novel null HLA-B allele, B*40:510N, due to a single nucleotide deletion in exon 2 Characterisation of the novel HLA-DPB1*04:02:24 allele by next-generation sequencing Prof. Alberto Piazza (1941–2024)
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