人格特质与 18 个月后抑郁状态的变化:英国精神病发病率调查的结果。

IF 4.9 2区 医学 Q1 CLINICAL NEUROLOGY Journal of affective disorders Pub Date : 2024-09-01 DOI:10.1016/j.jad.2024.08.190
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引用次数: 0

摘要

背景介绍抑郁症是一种常见的精神障碍,但其缓解率却很低。现有的证据表明,人格特质是与抑郁症病程相关的因素,但这些证据在方法上存在共同的局限性。找出与抑郁症相关的人格特质可以加深对抑郁症病程的理解。因此,我们旨在调查与 18 个月内抑郁症病程相关的人格特质。方法:分析了 2366 名成人精神病发病率调查受访者的纵向数据。在两个时间点(基线)和随访(约 18 个月后)进行了评估。我们评估了依赖型人格、强迫型人格和边缘型人格的结构化临床访谈(SCID-II)筛查问卷的总分。抑郁症的测量采用修订版临床访谈表(CIS-R):结果:与无抑郁组相比,边缘型人格量表基线得分每增加1分,持续抑郁几率增加1.50倍(OR = 1.50,95 % CI [1.22-1.86]),抑郁发病几率增加1.30倍(OR = 1.30,95 % CI [1.14-1.50]),康复几率增加1.52倍(OR = 1.52,95 % CI [1.35-1.70])。依赖型人格特质得分升高可显著预测抑郁的持续性(OR = 1.95,95 % CI [1.52-2.49])。强迫性人格量表得分每增加1分,抑郁症发病几率就会增加1.21倍(OR = 1.21, 95 % CI [1.04-1.39]):局限性:APMS 调查对抑郁状态的定义有限,这可能会影响这些结果的普遍性:本研究证实了之前的研究结果,并提供了人格功能障碍会加重抑郁症后果的证据。
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Personality traits and change in depression status at 18 months: Findings from a British Psychiatric Morbidity Survey

Background

Depression is a common mental disorder, yet it shows low remission rates. The available evidence on personality traits as factors associated with the course of depression has common methodological limitations. Identifying personality traits linked with depression can improve understanding of the course of illness. Therefore, we aimed to investigate personality traits that are associated with the course of depression over 18 months.

Methods

longitudinal data of 2366 Adult Psychiatric Morbidity Survey respondents were analysed. Assessments were applied at two-time points (baseline) and follow-up (about 18 months later). We assessed the total score on the screening questionnaire from the Structured Clinical Interview (SCID-II) for the dependent, obsessive-compulsive, and borderline personalities. Depression was measured using the revised Clinical Interview Schedule (CIS-R) version.

Results

An increase of one score on the borderline personality scale at baseline increased the odds of experiencing persistent depression by 1.50 times (OR = 1.50, 95 % CI [1.22–1.86]), depression onset by 1.30 times (OR = 1.30, 95 % CI [1.14–1.50]), and recovery by 1.52 times (OR = 1.52, 95 % CI [1.35–1.70]), comparing to no depression group. Elevated scores of dependent personality traits significantly predicted depression persistence (OR = 1.95, 95 % CI [1.52–2.49]). An increase of one score on the obsessive-compulsive personality scale increases the odds of depression onset by 1.21 times (OR = 1.21, 95 % CI [1.04–1.39]).

Limitations

The APMS survey defined depression statuses in a limited sense, which may affect the generalisability of these results.

Conclusion

The present study confirms previous findings and contributes evidence suggesting that personality dysfunctions worsen depression outcomes.

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来源期刊
Journal of affective disorders
Journal of affective disorders 医学-精神病学
CiteScore
10.90
自引率
6.10%
发文量
1319
审稿时长
9.3 weeks
期刊介绍: The Journal of Affective Disorders publishes papers concerned with affective disorders in the widest sense: depression, mania, mood spectrum, emotions and personality, anxiety and stress. It is interdisciplinary and aims to bring together different approaches for a diverse readership. Top quality papers will be accepted dealing with any aspect of affective disorders, including neuroimaging, cognitive neurosciences, genetics, molecular biology, experimental and clinical neurosciences, pharmacology, neuroimmunoendocrinology, intervention and treatment trials.
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