[急性草酸二甲酯中毒引起的急性肾损伤:病例报告]。

Y X Li, J R Zhang, Y J Feng
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引用次数: 0

摘要

草酸二甲酯是职业性有毒化学品之一,具有强烈的肾毒性。2023 年 5 月 16 日,定西市人民医院收治了一名急性草酸二甲酯中毒患者。患者表现为恶心、呕吐、腰胀、乏力、食欲不振、无尿,急性肾损伤进展迅速。肾活检证实为急性草酸盐肾病。经血液净化、抗氧化应激、糖皮质激素、补充液体、碱化尿液、抗感染、控制血压、补钙、纠正贫血等对症支持治疗后,患者症状消失,肾功能基本恢复正常。该病例提示,急性肾损伤患者必须明确病因,肾活检是重要的检查方法。对于急性草酸二甲酯中毒患者,应尽快进行以血液净化为基础的综合治疗,以改善预后。
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[Acute kidney injury caused by acute dimethyl oxalate poisoning: a case report].

Dimethyl oxalate is one of the occupational toxic chemicals and causes strong renal toxicity. On May 16, 2023, a patient with acute dimethyl oxalate poisoning was admitted to Dingxi People's Hospital. The patient presented with nausea, vomiting, lumbar distension, weakness, poor appetite, anuria, and rapidly progressing acute kidney injury. Renal biopsy confirmed acute oxalate nephropathy. After symptomatic supportive treatments such as blood purification, anti-oxidative stress, glucocorticoid, fluid supplementation, alkalized urine, anti-infection, controlling blood pressure, calcium supplementation and anemia correction, the patient's symptoms disappeared, and the kidney function basically returned to normal. This case suggested that the etiology of patients with acute kidney injury must be clearly identified, and renal biopsy was an important examination method. For patients suffering from acute dimethyl oxalate poisoning, comprehensive treatment based on blood purification should be performed as soon as possible, aiming to improve the prognosis.

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来源期刊
中华劳动卫生职业病杂志
中华劳动卫生职业病杂志 Medicine-Medicine (all)
CiteScore
1.00
自引率
0.00%
发文量
9764
期刊介绍:
期刊最新文献
[4 cases of occupational lung cancer caused by chloromethyl ether and dichloromethyl ether in a chemical enterprise]. [A case of acute pulmonary edema caused by exertional heat stroke]. [A case report of pulmonary aspergillosis secondary to occupational chronic formaldehyde toxic obstructive pulmonary disease]. [A meta-analysis of the prevalence of work-related musculoskeletal disorders among rehabilitation therapists]. [A meta-analysis of the relationship between overtime work and neck musculoskeletal disorders in Chinese occupational population].
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