用于血清诊断和治疗的多通道掺镧纳米探针。

IF 7 2区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Chemical record Pub Date : 2024-09-05 DOI:10.1002/tcr.202400100
Dr. Yuxin Liu, Zheng Wei
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引用次数: 0

摘要

在本文中,我们将重点介绍在开发用于高效血清诊断和治疗的多通道掺镧(MC-Ln)纳米探针方面的最新进展,尤其是我们自己的工作。首先,我们根据所含信号的类型和数量对 MC-Ln 纳米探针的类型进行了分类。阐明了不同类型纳米探针的优点以及使用镧系元素的原因。然后,我们概述了 MC-Ln 纳米探针目前在血清诊断和治疗中的应用,重点介绍了从不同角度提高诊断和治疗性能的战略探索。最后,我们对下一代 MC-Ln 纳米探针的未来发展和潜在问题进行了展望。我们希望这篇及时的文章能更新我们对 MC-Ln 和类似纳米探针在生物应用方面的认识,并为血清诊断和治疗的最新工具提供有益的参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Multichannel Lanthanide-Doped Nanoprobes for Serodiagnosis and Therapy

In this account, we will highlight recent progress in the development of multichannel lanthanide-doped (MC−Ln) nanoprobes for highly efficient serodiagnosis and therapy, with a particular focus on our own work. First, we first provide a classification of the types of MC−Ln nanoprobes based on the contained type and number of signals. The merits of different types of nanoprobes and the reason using lanthanides are elucidated. Then, we provide an overview of the current uses of MC−Ln nanoprobes in serodiagnosis and therapy, focusing on the strategic exploration to improve the diagnostic and therapeutic performance from different perspectives. Finally, we present a prospective outlook on the future development and potential issues of next-generation MC−Ln nanoprobes. We hope that this timely account will update our understanding of MC−Ln and similar nanoprobes for bioapplications and provide helpful references for the state-of-the-art tools for serodiagnosis and therapy.

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来源期刊
Chemical record
Chemical record 化学-化学综合
CiteScore
11.00
自引率
3.00%
发文量
188
审稿时长
>12 weeks
期刊介绍: The Chemical Record (TCR) is a "highlights" journal publishing timely and critical overviews of new developments at the cutting edge of chemistry of interest to a wide audience of chemists (2013 journal impact factor: 5.577). The scope of published reviews includes all areas related to physical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, polymer chemistry, materials chemistry, bioorganic chemistry, biochemistry, biotechnology and medicinal chemistry as well as interdisciplinary fields. TCR provides carefully selected highlight papers by leading researchers that introduce the author''s own experimental and theoretical results in a framework designed to establish perspectives with earlier and contemporary work and provide a critical review of the present state of the subject. The articles are intended to present concise evaluations of current trends in chemistry research to help chemists gain useful insights into fields outside their specialization and provide experts with summaries of recent key developments.
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