长期 COVID 症状和睡眠问题:一项基于人群的研究。

IF 3.4 3区 医学 Q2 CLINICAL NEUROLOGY Journal of Sleep Research Pub Date : 2024-09-05 DOI:10.1111/jsr.14327
Anna Letícia, Rosália Garcia Neves, Yohana Pereira Vieira, Tatiane Nogueira Gonzales, Melissa Marochi, Rodrigo Zopellaro Reis, Karla Pereira Machado, Suele Manjourany Silva Duro, Mirelle de Oliveira Saes
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引用次数: 0

摘要

调查巴西南部样本人群中2019年冠状病毒病(长COVID)长期影响症状与睡眠问题之间的关联。这项横断面研究使用了在巴西塞族共和国里奥格兰德市开展的 SULcovid-19 调查的数据。研究结果是通过 18 种症状的存在来调查长期 COVID,暴露变量是睡眠问题。采用对方差进行稳健调整的泊松回归来估算结果-暴露关系的粗略和调整流行率。通过对长 COVID 症状数量与睡眠问题之间的关系进行多项式回归,计算出患病率。分析已对性别、年龄、婚姻状况、收入、体重指数、吸烟状况、合并症和入院情况进行了调整。共对 2919 名成年人和老年人进行了访谈。长 COVID 患病率为 48.3%(95% 置信区间 [CI]:46.5-50.1%),41.2% 的样本报告有睡眠问题(95% 置信区间:39.4-43.0%)。有睡眠问题的人更有可能表现出敏感性改变(患病率比 [PR] 3.27;95% CI 1.96-5.45)、鼻塞(PR 2.75;95% CI 1.53-4.94)、肌肉骨骼症状(PR 1.75;95% CI 1.48-2.06)、呼吸问题(PR 1.58;95% CI 1.24-2.01)以及一种或多种长期 COVID 症状(PR 1.27;95% CI 1.15-1.39)。在接受分析的人群中,约有二分之一的人患有长COVID,10人中有4人表示有睡眠问题。此外,与那些报告睡眠良好的人相比,样本中出现的症状往往更多。
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Long COVID symptoms and sleep problems: a population-based study.

To investigate the association between symptoms of long-term effects of coronavirus disease 2019 (long COVID) and sleep problems in a sample population from southern Brazil. This cross-sectional study used data from the SULcovid-19 survey, developed in the municipality of Rio Grande, RS, Brazil. The outcome, long COVID, was investigated through the presence of 18 symptoms, and the exposure variable was sleep problems. Poisson regression with robust adjustment for variance was used to estimate crude and adjusted prevalence ratios for the outcome-exposure relationship. Odds ratio was calculated through multinomial regression of the relationship between the number of symptoms of long COVID and sleep problems. Analyses were adjusted for sex, age, marital status, income, body mass index, smoking status, comorbidities, and hospital admission. A total of 2919 adults and older adults were interviewed. The prevalence of long COVID was 48.3% (95% confidence interval [CI] 46.5-50.1%) and sleep problems were reported by 41.2% of the sample (95% CI 39.4-43.0%). Individuals with sleep problems were more likely to exhibit altered sensitivity (prevalence ratio [PR] 3.27; 95% CI 1.96-5.45), nasal congestion (PR 2.75; 95% CI 1.53-4.94), musculoskeletal symptoms (PR 1.75; 95% CI 1.48-2.06), respiratory issues (PR 1.58; 95% CI 1.24-2.01), and one or more symptom of long COVID (PR 1.27; 95% CI 1.15-1.39). Approximately one-half of the population analysed had long COVID, and four of 10 reported experiencing sleep problems. In addition, the sample tended to have experienced a greater number of symptoms compared with those who reported to sleep well.

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来源期刊
Journal of Sleep Research
Journal of Sleep Research 医学-临床神经学
CiteScore
9.00
自引率
6.80%
发文量
234
审稿时长
6-12 weeks
期刊介绍: The Journal of Sleep Research is dedicated to basic and clinical sleep research. The Journal publishes original research papers and invited reviews in all areas of sleep research (including biological rhythms). The Journal aims to promote the exchange of ideas between basic and clinical sleep researchers coming from a wide range of backgrounds and disciplines. The Journal will achieve this by publishing papers which use multidisciplinary and novel approaches to answer important questions about sleep, as well as its disorders and the treatment thereof.
期刊最新文献
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