伊斯法罕省《非酒精性脂肪肝患者肝纤维化评估临床实践指南》改编。

IF 1.7 Q2 MEDICINE, GENERAL & INTERNAL International Journal of Preventive Medicine Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI:10.4103/ijpvm.ijpvm_284_22
Sayed Mohammad Hosseeini, Mohammad Jafari, Marzieh Tahmasebi, Payman Adibi
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引用次数: 0

摘要

非酒精性脂肪肝(NAFLD)是指肝脏脂肪变性(脂肪在肝脏中的堆积超过肝脏重量的 5%),但没有导致肝脏脂肪堆积的继发性原因,如过度饮酒。非酒精性脂肪肝分为两种类型:非酒精性脂肪肝(NAFL)和非酒精性脂肪性肝炎(NASH)。因此,在本临床指南中,我们试图确定该疾病的一般和重要政策,并修改其治疗方法。我们对伊斯法罕省的非酒精性脂肪肝管理指南进行了调整。本指南是通过临床评估、证据审查、现有临床指南以及与伊朗胃肠病学和肝脏病学协会伊斯法罕分会成员协商后制定的。活组织检查被推荐为诊断非酒精性脂肪肝患者脂肪性肝炎和纤维化的最可靠方法(金标准)。与其他血清学检测相比,非酒精性脂肪肝纤维化评分(NFS)和纤维化-4(FIB-4)被推荐为对非酒精性脂肪肝患者晚期纤维化具有最高预测价值的检测方法。在用于评估肝纤维化的无创方法中,瞬态弹性成像(TE)优于其他方法。
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Adaptation of Clinical Practice Guideline for Assessment of Liver Fibrosis in Patients with Non Alcoholic Fatty Liver Disease in Isfahan Province.

Non-alcoholic fatty liver disease (NAFLD) refers to the presence of hepatic steatosis (accumulation of fat in the liver to over 5% of its weight) in the absence of secondary causes of fat accumulation in the liver such as excessive alcohol use. NAFLD is divided into two types: non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH). Therefore, in this clinical guideline, we sought to determine general and important policies for this disease and modify its managment approaches. We adapted this guideline for the management of NAFLD in Isfahan Province. This guideline was developed by clinical appraisal and review of the evidence, available clinical guidelines, and in consultation with members of the Isfahan Chamber of the Iranian Association of Gastroenterology and Hepatology. Biopsy is recommended as the most reliable method (gold standard) to diagnose steatohepatitis and fibrosis in patients with NAFLD. NAFLD fibrosis score (NFS) and fibrosis-4 (FIB-4) are recommended as the test with the highest predictive value for advanced fibrosis in patients with NAFLD compared to other serologic tests. Among the noninvasive methods used to assess liver fibrosis, transient elastography (TE) is preferable to other methods.

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来源期刊
International Journal of Preventive Medicine
International Journal of Preventive Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
3.20
自引率
4.80%
发文量
107
期刊介绍: International Journal of Preventive Medicine, a publication of Isfahan University of Medical Sciences, is a peer-reviewed online journal with Continuous print on demand compilation of issues published. The journal’s full text is available online at http://www.ijpvmjournal.net. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository. The journal will cover technical and clinical studies related to health, ethical and social issues in field of Preventive Medicine. Articles with clinical interest and implications will be given preference.
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