将 2-氨基苯并噻唑应用于多组分合成杂环的最新进展。

IF 2.5 4区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY ChemistryOpen Pub Date : 2024-09-09 DOI:10.1002/open.202400185
Ramin Javahershenas, Jianlin Han, Mosstafa Kazemi, Peter J Jervis
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引用次数: 0

摘要

杂环化合物是药物研发、农业和材料科学等众多领域的重要化合物。高效的杂环合成方法对于满足这些行业的需求仍然至关重要。利用 2-氨基苯并噻唑(ABT)进行多组分反应(MCR)的最新进展表明,在合成杂环方面取得了可喜的成果。2-氨基苯并噻唑在这方面的多功能性使其能够快速高效地构建各种杂环结构。本文讨论了涉及 2-氨基苯并噻唑的各种合成方法和反应,强调了它作为复杂杂环合成的重要构件的重要性。此外,还探讨了这些杂环在药物发现和材料科学中的潜在应用。总之,本综述全面概述了该领域的研究现状,并对这一前景广阔的研究领域的未来发展方向提出了见解。我们强调了 ABT 作为通过 MCR 进行杂环合成的多功能和可持续起始材料的潜力,这对化学工业具有重大意义。
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Recent Advances in the Application of 2-Aminobenzothiazole to the Multicomponent Synthesis of Heterocycles.

Heterocycles are a vital class of compounds in numerous fields, including drug discovery, agriculture, and materials science. Efficient methods for the synthesis of heterocycles remain critical for meeting the demands of these industries. Recent advances in multicomponent reactions (MCRs) utilizing 2-aminobenzothiazole (ABT) have shown promising results for the formation of heterocycles. The versatility of 2-aminobenzothiazole in this context has enabled the rapid and efficient construction of diverse heterocyclic structures. Various synthetic methodologies and reactions involving 2-aminobenzothiazole are discussed, highlighting its importance as a valuable building block in the synthesis of complex heterocycles. The potential applications of these heterocycles in drug discovery and material science are also explored. Overall, this review provides a comprehensive overview of the current state of research in the field and offers insights into the future directions of this promising area of study. We highlight the potential of ABT as a versatile and sustainable starting material in heterocyclic synthesis via MCRs, with significant implications for the chemical industry.

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来源期刊
ChemistryOpen
ChemistryOpen CHEMISTRY, MULTIDISCIPLINARY-
CiteScore
4.80
自引率
4.30%
发文量
143
审稿时长
1 months
期刊介绍: ChemistryOpen is a multidisciplinary, gold-road open-access, international forum for the publication of outstanding Reviews, Full Papers, and Communications from all areas of chemistry and related fields. It is co-owned by 16 continental European Chemical Societies, who have banded together in the alliance called ChemPubSoc Europe for the purpose of publishing high-quality journals in the field of chemistry and its border disciplines. As some of the governments of the countries represented in ChemPubSoc Europe have strongly recommended that the research conducted with their funding is freely accessible for all readers (Open Access), ChemPubSoc Europe was concerned that no journal for which the ethical standards were monitored by a chemical society was available for such papers. ChemistryOpen fills this gap.
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