体重指数升高与肩袖疾病有关:系统回顾与元分析

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引用次数: 0

摘要

目的 分析有关肥胖、体重指数(BMI)和肩袖疾病(RCD)的文献。方法 在本系统综述和荟萃分析中,我们使用关键词查询了 PubMed、Embase、Cochrane、Cumulative Index to Nursing & Allied Health 和 Science Direct(2023 年 8 月 25 日)。符合纳入条件的分析性观察研究(队列研究、病例对照研究和横断面研究)中,每个对比组的参与人数超过 30 人,这些研究评估了肥胖与肩袖病变之间的关系。我们进行了 Meta 分析,定量总结了 BMI 与 RCD 之间的关联,报告了基于回归模型的几率和相应的 95% 置信区间 (CI),以及病例和对照组之间的 BMI 平均差异。在对 248 篇文章进行全文审阅后,有 27 篇文章提供了肥胖与 RCD 的数据,其中 17 篇符合荟萃分析的条件。与无 RCD 的人相比,有 RCD 的人超重的可能性是无 RCD 的人的 1.21 倍(95% CI 1.10-1.34),肥胖的可能性是无 RCD 的人的 1.44 倍(95% CI 1.32-1.59)。体重指数每增加 5 个单位,肩袖撕裂的几率就会增加 35% (95% CI 1.06-1.71)。对偏倚风险的深入评估显示,各项研究的质量差异很大,并强调结果异质性、缺乏时间性、混杂因素和选择偏倚是各项研究的主要问题。
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Elevated Body Mass Index Is Associated With Rotator Cuff Disease: A Systematic Review and Meta-analysis

Purpose

To analyze the literature regarding obesity, body mass index (BMI), and rotator cuff disease (RCD).

Methods

In this Systematic Review and Meta-analysis, we queried PubMed, Embase, Cochrane, Cumulative Index to Nursing & Allied Health, and Science Direct using key words (August 25, 2023). Analytic observational studies (cohort, case-control, and cross-sectional studies) with more than 30 participants per comparison group, evaluating the association between obesity and rotator cuff pathology, were eligible for inclusion. Meta-analysis was performed to quantitatively summarize associations between BMI and RCD to report odds ratios and corresponding 95% confidence intervals (CIs) for regression-based models and BMI mean differences between cases and controls. Risk Of Bias In Non-randomised Studies – of Interventions tool was used to evaluate risk of bias across all studies in the systematic review.

Results

After full-text review of 248 articles, 27 presented data on obesity and RCD, and 17 qualified for meta-analysis. Individuals with RCD were 1.21 times (95% CI 1.10-1.34) as likely to have overweight and 1.44 times (95% CI 1.32-1.59) as likely to have obesity compared with those without RCD. Each 5-unit increase in BMI was associated with 35% greater odds of having rotator cuff tear (95% CI 1.06-1.71). In-depth assessment for risk of bias shows quality of studies varies greatly and highlights outcome heterogeneity, lack of temporality, confounding and selection bias as major concerns for individual studies.

Conclusions

In this study, we found a positive association between elevated BMI and RCD.

Level of Evidence

Level III, systematic review and meta-analysis of Level II-III studies.

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来源期刊
CiteScore
2.70
自引率
0.00%
发文量
218
审稿时长
45 weeks
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