犬乳腺癌:诊断和治疗策略的最新进展

IF 3.7 4区 医学 Q2 PHARMACOLOGY & PHARMACY Advanced Therapeutics Pub Date : 2024-08-16 DOI:10.1002/adtp.202400115
Pritish Rath, Chitra Jaiswal, Debajyoti Pal, Samit Kumar Nandi, Biman B. Mandal
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摘要

犬类乳腺癌是全球死亡的主要原因之一,原因在于客户的误解以及诊断和治疗不当。在过去的几个世纪里,犬乳腺癌的诊断和治疗沿用了人类肿瘤学的传统技术。然而,随着未来需求的增加和科学的进步,对犬乳腺癌(CBC)患者的诊断和治疗进行现代化的必要性正在显现。本综述探讨了诊断技术和新型治疗方法的最新进展,如辅助靶向疗法、纳米材料疗法、免疫疗法、收养细胞疗法、肿瘤疫苗、溶瘤病毒疗法以及非编码 RNA 在 CBC 中的应用。此外,综述还讨论了旨在提高诊断和治疗效果的医疗保健政策,以及将人类肿瘤学转化为兽医肿瘤学的未来方向。通过采用这些现代策略,将其转化为实际应用,可显著提高医疗质量,为犬病患者带来更好的治疗效果和更高的生存率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Canine Breast Carcinomas: Recent Advances in Diagnostic and Treatment Strategies

Breast cancer in canines is one of the leading causes of death globally due to client misinterpretation and improper diagnosis and treatment. In past centuries, the diagnosis and treatment of breast carcinoma in dogs followed conventional techniques adopted from human oncology. However, with increasing demand and scientific advancements in the upcoming future, there is an emerging necessity to modernize the diagnostic and treatments in canine breast cancer (CBC) patients. This review explores recent advances in diagnostic techniques and novel therapeutic approaches such as adjuvant-based targeted therapy, nanomaterial therapy, immune-based therapy, adoptive cell therapy, tumor vaccine, oncolytic virotherapy, and the use of noncoding RNAs in CBCs. In addition, the review discusses the healthcare policies aimed at improving diagnostic and therapeutic efficacy and future directions for translation from human oncology into veterinary oncology. By adopting these modern strategies, the quality of care can be significantly enhanced by translating them into practical applications with better outcomes and improved survival rates for canine patients.

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来源期刊
Advanced Therapeutics
Advanced Therapeutics Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
7.10
自引率
2.20%
发文量
130
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