离子液体中的金（III）催化：香豆素合成案例研究

IF 4.4 2区化学 Q2 CHEMISTRY, APPLIED Advanced Synthesis & Catalysis Pub Date : 2025-01-07 DOI:10.1002/adsc.202400706

Francesco Ravera , Marte Sofie Martinsen Holmsen , Paolo Sgarbossa , Didier Bourissou , Andrea Biffis

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引用次数: 0

摘要

事实证明，在温和实用的条件下（0.1-2 摩尔催化剂、25-40°C、1-24 小时），定义明确的 (P,C)- 环甲基化 Au(III) 复合物能够通过分子内羟基化多种芳基丙醇酯来催化香豆素的合成。使用离子液体作为反应溶剂可以大大减少用于催化剂再生步骤的布伦氏酸的用量。对酸添加剂和离子液体阴离子性质的影响进行了评估。此外，还介绍了将这种方法推广到芳基丙炔醚环化的初步结果。

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Gold(III) Catalysis in Ionic Liquids: The Case Study of Coumarin Synthesis

Well‐defined (P,C)‐cyclometalated Au(III) complexes proved to be able to catalyze the synthesis of coumarins by intramolecular hydroarylation of a broad range of aryl propiolates under mild and practical conditions (0.1–2 mol% catalyst, 25–40 °C, 1–24 hours). The use of an ionic liquid as reaction solvent allowed to drastically decrease the amount of Brönsted acid used to unlock the catalyst regeneration step. The effect of the nature of the acid additive and of the ionic liquid anion have been assessed. Preliminary results on the extension of this methodology to the cyclization of aryl propargyl ethers are also presented.

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来源期刊

Advanced Synthesis & Catalysis 化学-应用化学

CiteScore

9.40

自引率

7.40%

发文量

447

审稿时长

1.8 months

期刊介绍： Advanced Synthesis & Catalysis (ASC) is the leading primary journal in organic, organometallic, and applied chemistry. The high impact of ASC can be attributed to the unique focus of the journal, which publishes exciting new results from academic and industrial labs on efficient, practical, and environmentally friendly organic synthesis. While homogeneous, heterogeneous, organic, and enzyme catalysis are key technologies to achieve green synthesis, significant contributions to the same goal by synthesis design, reaction techniques, flow chemistry, and continuous processing, multiphase catalysis, green solvents, catalyst immobilization, and recycling, separation science, and process development are also featured in ASC. The Aims and Scope can be found in the Notice to Authors or on the first page of the table of contents in every issue.