腺性牙源性囊肿引发的低级别粘液表皮样癌:病例报告与文献综述

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摘要

低级别粘液表皮样癌(MEC)是一种很少发生在颌骨内的唾液腺肿瘤。由于其组织病理学特征与牙源性腺囊肿(GOC)有相当多的重叠,因此给诊断带来了挑战。人们提出了各种理论来解释中枢性低级别 MEC 的起源,其中一种可能的理论是 MEC 源于 GOC 的内膜。本文报告了一例 54 岁女性的下颌前区多形性病变,该病变在临床和显微镜下与腺性牙源性囊肿相似,但根据免疫组化鉴定最终确诊为低级别 MEC。
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Low grade mucoepidermoid carcinoma arising from glandular odontogenic cyst: A case report with a brief literature review

Low-grade mucoepidermoid carcinoma (MEC) is a salivary gland tumor arising rarely within the jaw bones. It poses a diagnostic challenge due to its considerable overlap of the histopathological features with Glandular odontogenic cyst (GOC). Various theories have been put forward to explain the origin of central low-grade MEC, one of the potential being MEC arising from the lining of GOC. In the present paper we report a case of a multilocular lesion in a 54-year-old female in the mandibular anterior region, which clinically and microscopically had a resemblance to the glandular odontogenic cyst, but the final diagnosis of low-grade MEC was confirmed based on the immunohistochemical appraisal.

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