三维生物打印在癌症应用领域的最新进展和挑战

Q1 Computer Science Bioprinting Pub Date : 2024-09-13 DOI:10.1016/j.bprint.2024.e00357
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引用次数: 0

摘要

三维生物打印已成为一项前景广阔的技术,在癌症研究和治疗方面具有变革潜力。本综述探讨了三维生物打印技术在癌症领域的创新应用、挑战和未来发展方向。通过再现肿瘤微环境和异质性,三维生物打印模型为研究癌症生物学、药物反应和个性化医疗提供了宝贵的平台。三维生物打印与其他尖端技术(如芯片上器官和微流控技术)的整合进一步增强了复制肿瘤动态和异质性的能力。未来的发展方向包括生物材料工程、生物打印技术和跨学科合作方面的进步,以克服这些挑战。将三维生物打印技术融入临床实践,有望彻底改变癌症诊断、治疗和管理。
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Recent advancements and challenges in 3D bioprinting for cancer applications

3D bioprinting has emerged as a promising technology with transformative potential in cancer research and therapy. This review explores the innovative applications, challenges, and future directions of 3D bioprinting in the field of cancer. By recapitulating tumor microenvironments and heterogeneity, 3D bioprinted models offer valuable platforms for studying cancer biology, drug responses, and personalized medicine. The integration of 3D bioprinting with other cutting-edge technologies, such as organ-on-a-chip and microfluidics, has further enhanced the ability to replicate the dynamic and heterogeneous nature of tumors. The forthcoming paths include advancements in biomaterial engineering, bioprinting techniques, and interdisciplinary collaborations to overcome these challenges. Integration of 3D bioprinting into clinical practice holds promise for revolutionizing cancer diagnosis, treatment, and management.

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来源期刊
Bioprinting
Bioprinting Computer Science-Computer Science Applications
CiteScore
11.50
自引率
0.00%
发文量
72
审稿时长
68 days
期刊介绍: Bioprinting is a broad-spectrum, multidisciplinary journal that covers all aspects of 3D fabrication technology involving biological tissues, organs and cells for medical and biotechnology applications. Topics covered include nanomaterials, biomaterials, scaffolds, 3D printing technology, imaging and CAD/CAM software and hardware, post-printing bioreactor maturation, cell and biological factor patterning, biofabrication, tissue engineering and other applications of 3D bioprinting technology. Bioprinting publishes research reports describing novel results with high clinical significance in all areas of 3D bioprinting research. Bioprinting issues contain a wide variety of review and analysis articles covering topics relevant to 3D bioprinting ranging from basic biological, material and technical advances to pre-clinical and clinical applications of 3D bioprinting.
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