{"title":"通过 \"开启 \"响应实现 Pb2+、Mg2+ 和 Al3+ 离子多功能检测的 ESIPT 性能双希夫碱及其生物应用","authors":"Lu Li, Jianing Zhao, Chengwei Lü","doi":"10.1007/s11164-024-05386-3","DOIUrl":null,"url":null,"abstract":"<div><p>Benzothiazole, hydrazine/ammonia and salicylaldehyde were selected as basic unit for constructing of bis-Schiff base molecules with excited state intramolecular proton transfer (ESIPT) property. Herein, “turn-on” fluorescent performance and highly sensitive multifunctional fluorescence probes were developed to stably and efficiently detect Pb<sup>2+</sup>, Mg<sup>2+</sup> and Al<sup>3+</sup> in biological and environmental samples. Among them, BF-SJ could distinguish Pb<sup>2+</sup> and Mg<sup>2+</sup> ions under different pH conditions, while BF-SO could separate Pb<sup>2+</sup> and Al<sup>3+</sup> by different emission wavelength. More important, target ions could be distinguished by naked eyes with color change of solution under sun light and ultraviolet lamp. The LOD values of BF-SJ and BF-SO for Pb<sup>2+</sup>/Mg<sup>2+</sup> and Pb<sup>2+</sup>/Al<sup>3+</sup> were as low as 31.23 μM, 25.95 μM, 59.57 μM and 1.38 μM, respectively. Ideally, they showed low cytotoxicity and were successfully used for imaging of exogenous Pb<sup>2+</sup>/Mg<sup>2+</sup> and Pb<sup>2+</sup>/Al<sup>3+</sup> in HeLa cells. Also, BF-SJ exhibited satisfactory performance in detection of Mg<sup>2+</sup> in seawater and test paper experiment.</p><h3>Graphical abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":753,"journal":{"name":"Research on Chemical Intermediates","volume":"50 10","pages":"5017 - 5038"},"PeriodicalIF":2.8000,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ESIPT performance bis-Schiff base for multifunctional detection of Pb2+, Mg2+ and Al3+ ions through “turn-on” response and its biological application\",\"authors\":\"Lu Li, Jianing Zhao, Chengwei Lü\",\"doi\":\"10.1007/s11164-024-05386-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Benzothiazole, hydrazine/ammonia and salicylaldehyde were selected as basic unit for constructing of bis-Schiff base molecules with excited state intramolecular proton transfer (ESIPT) property. Herein, “turn-on” fluorescent performance and highly sensitive multifunctional fluorescence probes were developed to stably and efficiently detect Pb<sup>2+</sup>, Mg<sup>2+</sup> and Al<sup>3+</sup> in biological and environmental samples. Among them, BF-SJ could distinguish Pb<sup>2+</sup> and Mg<sup>2+</sup> ions under different pH conditions, while BF-SO could separate Pb<sup>2+</sup> and Al<sup>3+</sup> by different emission wavelength. More important, target ions could be distinguished by naked eyes with color change of solution under sun light and ultraviolet lamp. The LOD values of BF-SJ and BF-SO for Pb<sup>2+</sup>/Mg<sup>2+</sup> and Pb<sup>2+</sup>/Al<sup>3+</sup> were as low as 31.23 μM, 25.95 μM, 59.57 μM and 1.38 μM, respectively. Ideally, they showed low cytotoxicity and were successfully used for imaging of exogenous Pb<sup>2+</sup>/Mg<sup>2+</sup> and Pb<sup>2+</sup>/Al<sup>3+</sup> in HeLa cells. Also, BF-SJ exhibited satisfactory performance in detection of Mg<sup>2+</sup> in seawater and test paper experiment.</p><h3>Graphical abstract</h3>\\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>\",\"PeriodicalId\":753,\"journal\":{\"name\":\"Research on Chemical Intermediates\",\"volume\":\"50 10\",\"pages\":\"5017 - 5038\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2024-09-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Research on Chemical Intermediates\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s11164-024-05386-3\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research on Chemical Intermediates","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s11164-024-05386-3","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
ESIPT performance bis-Schiff base for multifunctional detection of Pb2+, Mg2+ and Al3+ ions through “turn-on” response and its biological application
Benzothiazole, hydrazine/ammonia and salicylaldehyde were selected as basic unit for constructing of bis-Schiff base molecules with excited state intramolecular proton transfer (ESIPT) property. Herein, “turn-on” fluorescent performance and highly sensitive multifunctional fluorescence probes were developed to stably and efficiently detect Pb2+, Mg2+ and Al3+ in biological and environmental samples. Among them, BF-SJ could distinguish Pb2+ and Mg2+ ions under different pH conditions, while BF-SO could separate Pb2+ and Al3+ by different emission wavelength. More important, target ions could be distinguished by naked eyes with color change of solution under sun light and ultraviolet lamp. The LOD values of BF-SJ and BF-SO for Pb2+/Mg2+ and Pb2+/Al3+ were as low as 31.23 μM, 25.95 μM, 59.57 μM and 1.38 μM, respectively. Ideally, they showed low cytotoxicity and were successfully used for imaging of exogenous Pb2+/Mg2+ and Pb2+/Al3+ in HeLa cells. Also, BF-SJ exhibited satisfactory performance in detection of Mg2+ in seawater and test paper experiment.
期刊介绍：
Research on Chemical Intermediates publishes current research articles and concise dynamic reviews on the properties, structures and reactivities of intermediate species in all the various domains of chemistry.
The journal also contains articles in related disciplines such as spectroscopy, molecular biology and biochemistry, atmospheric and environmental sciences, catalysis, photochemistry and photophysics. In addition, special issues dedicated to specific topics in the field are regularly published.
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