预防产伤导致的尿失禁问题的干预措施的临床和成本效益:快速审查

Bethany Fern Anthony, Jacob Davies, Kalpa Pisavadia, Sofie Roberts, Llinos Haf Spencer, Elizabeth Gillen, Juliet Hounsome, Jane C Noyes, Dyfrig A Hughes, Deborah Fitzsimmons, Rhiannon Tudor Edwards, Adrian G Edwards, Alison Cooper, Ruth Lewis
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引用次数: 0

摘要

尿失禁和大便失禁通常与分娩时的压力和紧张有关,尤其是会阴部创伤,这种情况会使人衰弱,严重影响妇女的生活质量。在英国,大约 85% 的阴道分娩都会受到与分娩相关的会阴创伤的影响,这些创伤可能是自然造成的,也可能是外阴切开术造成的。尿失禁也给医疗系统带来了巨大的经济负担。根据之前的估算,仅压力性尿失禁一项每年就会给英国国民健康服务系统(NHS)造成 1.77 亿英镑的损失。本次快速审查旨在找出有关预防分娩创伤导致的尿失禁问题的干预措施的临床有效性和成本效益的证据。本综述纳入了 2023 年至 2024 年间发表的 23 项研究:其中包括 20 篇临床有效性系统综述和 3 篇经济评估。研究结果支持对产前和产后妇女进行运动干预,包括盆底肌肉训练,以预防尿失禁。然而,支持其长期有效性的证据有限。尿失禁是一种潜在的长期负担,因为怀孕和分娩会削弱骨盆底肌,使妇女在以后的生活中更容易出现尿失禁。由于荷尔蒙的变化以及骨盆底肌肉的进一步减弱,更年期往往会加剧这些问题。非运动型干预措施,如产前会阴按摩和阴道装置,在现有的证据库中较少出现,尤其是对大便失禁结果而言。对尿失禁干预措施的成本效益进行评估的经济评价很少,但是,尿失禁对国家医疗服务体系造成了巨大的经济负担,因此有必要对临床有效的预防性方案进行投资。我们的研究结果表明,有必要对以运动为基础的干预措施进行投资。还需要进一步的研究来评估运动疗法的维持效果和长期效果。还需要进行更多的研究,重点关注替代型干预措施和粪便失禁的预防。未来的审查需要考虑妇女经验的定性研究结果,以及推出预防尿失禁干预措施的可接受性和可行性。
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The clinical and cost-effectiveness of interventions for preventing continence issues resulting from birth trauma: a rapid review
Urinary and faecal incontinence, which are often linked to the stresses and strains of childbirth, particularly perineal trauma, are debilitating conditions that can significantly impact womens quality of life. Approximately 85% of vaginal births in the United Kingdom (UK) are affected by childbirth related perineal trauma, either spontaneously or due to episiotomy. Incontinence also places a significant financial burden on the healthcare system. Previous estimates have shown that stress urinary incontinence alone costs the National Health Service (NHS) 177 million UK pounds per year. The aim of this rapid review was to identify evidence on the clinical effectiveness and cost-effectiveness of interventions for preventing continence issues resulting from birth trauma. Twenty-three studies, published between 2023 and 2024, were included in this review: 20 systematic reviews of clinical effectiveness and three economic evaluations. A number of key findings, research implications and evidence gaps were identified. The findings support the use of exercise-based interventions including pelvic floor muscle training for prenatal and postnatal women to prevent urinary incontinence. However, there is limited evidence supporting their long-term effectiveness. Incontinence is a potential long-term burden as pregnancy and childbirth can weaken the pelvic floor, making women more susceptible to incontinence in later life. Menopause often exacerbates these issues due to hormonal changes and by further weakening the pelvic floor muscles. Non exercise-based interventions, such as prenatal perineal massage and vaginal devices were less represented in the available evidence base, especially for faecal incontinence outcomes. There was a paucity of economic evaluations assessing the cost-effectiveness of interventions for incontinence, however, the substantial economic burden of incontinence on the NHS necessitates investment in clinically effective, preventative options. Our findings present the case for investing in exercise-based interventions. Further research is needed to evaluate the maintenance and long-term effects of exercise-based therapy. More research is also needed that focus on alternative type interventions and the prevention of faecal incontinence. Future reviews need to consider qualitative findings of womens experiences and the acceptability and feasibility of rolling out interventions for the prevention of incontinence.
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