增强现实导航系统(SIRIO)用于椎体肿瘤消融术中的神经损伤治疗

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-08-30 DOI:10.3390/curroncol31090376
Eliodoro Faiella, Rebecca Casati, Matteo Pileri, Giuseppina Pacella, Carlo Altomare, Elva Vergantino, Amalia Bruno, Bruno Beomonte Zobel, Rosario Francesco Grasso
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引用次数: 0

摘要

(1)本研究评估了CT引导下的SIRIO增强现实导航系统对原发性和转移性骨肿瘤椎体热消融(RTA)手术疗效和神经保护临床结果的影响。(2)方法:对28例椎体RTA手术进行了回顾性非随机分析,比较了12例SIRIO辅助手术和16例非SIRIO辅助手术。主要结果包括剂量-长度乘积(DLP)和硬膜外剥离时间。次要结果包括技术成功率、并发症发生率以及手术时间(VAS 时间 0)和术后三个月(VAS 时间 1)的疼痛评分。统计分析包括 t 检验、曼-惠特尼 U 检验和多元回归。(3) 结果:与非 SIRIO 辅助手术相比,SIRIO 辅助手术显著减少了 DLP(307.42 mGycm vs. 460.31 mGycm,p = 2.23 × 10-8)和手术硬膜外剥离时间(13.48 分钟 vs. 32.26 分钟,p = 2.61 × 10-12)。多元回归证实了这些减少是显著的(DLP:β = -162.38, p < 0.001;时间:β = -18.25,p < 0.001)。疼痛评分(VAS 时间 1)在组间无明显差异,肿瘤类型对结果无明显影响。(4) 结论:SIRIO 系统提高了神经保护的有效性和安全性,减少了脊柱肿瘤消融过程中的辐射剂量和手术时间,同时保持了一致的疼痛治疗效果。
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Augmented Reality Navigation System (SIRIO) for Neuroprotecion in Vertebral Tumoral Ablation
(1) This study evaluates the impact of the CT-guided SIRIO augmented reality navigation system on the procedural efficacy and clinical outcomes of neuroprotection in vertebral thermal ablation (RTA) for primary and metastatic bone tumors. (2) Methods: A retrospective non-randomized analysis of 28 vertebral RTA procedures was conducted, comparing 12 SIRIO-assisted and 16 non-SIRIO-assisted procedures. The primary outcomes included dose-length product (DLP) and epidural dissection time. The secondary outcomes included technical success, complication rates, and pain scores at procedural time (VAS Time 0) and three months post-procedure (VAS Time 1). The statistical analyses included t-tests, Mann–Whitney U tests, and multiple regression. (3) Results: SIRIO-assisted procedures significantly reduced DLP (307.42 mGycm vs. 460.31 mGycm, p = 2.23 × 10−8) and procedural epidural dissection time (13.48 min vs. 32.26 min, p = 2.61 × 10−12) compared to non-SIRIO-assisted procedures. Multiple regression confirmed these reductions were significant (DLP: β = −162.38, p < 0.001; time: β = −18.25, p < 0.001). Pain scores (VAS Time 1) did not differ significantly between groups, and tumor type did not significantly influence outcomes. (4) Conclusions: The SIRIO system enhances neuroprotection efficacy and safety, reducing radiation dose and procedural time during spine tumoral ablation while maintaining consistent pain management outcomes.
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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