{"title":"一名下颌角弓反张症患儿因使用益生菌引起的副溶血性乳酸杆菌菌血症：病例报告与文献综述。","authors":"Kohei Ukai,Koh Okamoto,Akinori Ichinose,Mariko Yoshida,Yoshimi Higurashi,Ryu Yoneda,Shuta Yamamoto,Takashi Asahara","doi":"10.1097/inf.0000000000004548","DOIUrl":null,"url":null,"abstract":"Probiotics are generally considered safe and used to improve intestinal function. Here, we report a Lacticaseibacillus paracasei bacteremia case in an 8-month-old girl administered probiotics containing L. paracasei after jejunostomy for hypoganglionosis. The patient had persistent bacteremia with L. paracasei and was treated with antimicrobial therapy. The isolate from the blood culture was genetically indistinguishable to the strain contained in probiotics. Bacteremia risk should be considered before probiotic use in patients with underlying compromised immune systems or intestinal integrity.","PeriodicalId":501652,"journal":{"name":"The Pediatric Infectious Disease Journal","volume":"153 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Lacticaseibacillus paracasei Bacteremia Associated With Probiotic Use in a Child With Hypoganglionosis: Case Report and Literature Review.\",\"authors\":\"Kohei Ukai,Koh Okamoto,Akinori Ichinose,Mariko Yoshida,Yoshimi Higurashi,Ryu Yoneda,Shuta Yamamoto,Takashi Asahara\",\"doi\":\"10.1097/inf.0000000000004548\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Probiotics are generally considered safe and used to improve intestinal function. Here, we report a Lacticaseibacillus paracasei bacteremia case in an 8-month-old girl administered probiotics containing L. paracasei after jejunostomy for hypoganglionosis. The patient had persistent bacteremia with L. paracasei and was treated with antimicrobial therapy. The isolate from the blood culture was genetically indistinguishable to the strain contained in probiotics. Bacteremia risk should be considered before probiotic use in patients with underlying compromised immune systems or intestinal integrity.\",\"PeriodicalId\":501652,\"journal\":{\"name\":\"The Pediatric Infectious Disease Journal\",\"volume\":\"153 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Pediatric Infectious Disease Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/inf.0000000000004548\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Pediatric Infectious Disease Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/inf.0000000000004548","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Lacticaseibacillus paracasei Bacteremia Associated With Probiotic Use in a Child With Hypoganglionosis: Case Report and Literature Review.
Probiotics are generally considered safe and used to improve intestinal function. Here, we report a Lacticaseibacillus paracasei bacteremia case in an 8-month-old girl administered probiotics containing L. paracasei after jejunostomy for hypoganglionosis. The patient had persistent bacteremia with L. paracasei and was treated with antimicrobial therapy. The isolate from the blood culture was genetically indistinguishable to the strain contained in probiotics. Bacteremia risk should be considered before probiotic use in patients with underlying compromised immune systems or intestinal integrity.
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