从基因组学角度了解 mRNA COVID-19 疫苗的功效：将基因多态性与免疫力下降联系起来

IF 4.8 4区医学 Human Vaccines & Immunotherapeutics Pub Date : 2024-09-10 DOI:10.1080/21645515.2024.2399382

Min-Jia Hsieh, Ping-Hsing Tsai, Pin-Hsuan Chiang, Zih-Kai Kao, Zi-Qing Zhuang, Ai-Ru Hsieh, Hsiang-Ling Ho, Shih-Hwa Chiou, Kung-Hao Liang, Yu-Chun Chen

引用次数: 0

摘要

基因多态性与接种疫苗后COVID-19疫苗诱导免疫力的不同减弱有关。尽管如此，关于这种免疫力减弱背后的机制的证据仍然缺乏。

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Genomic insights into mRNA COVID-19 vaccines efficacy: Linking genetic polymorphisms to waning immunity

Genetic polymorphisms have been linked to the differential waning of vaccine-induced immunity against COVID-19 following vaccination. Despite this, evidence on the mechanisms behind this waning and...

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来源期刊

Human Vaccines & Immunotherapeutics BIOTECHNOLOGY & APPLIED MICROBIOLOGY-IMMUNOLOGY

自引率

8.30%

发文量

审稿时长

1 months

期刊介绍： (formerly Human Vaccines; issn 1554-8619) Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics. Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.