{"title":"使用蒙特卡洛和 MIRD 方法计算注射 99m锝-HMPAO、99m锝-DMSA 和 99m锝-硫胶体患者的吸收剂量","authors":"Farzane Mohajeri, Ahad Ollah Ezzati","doi":"10.1007/s10967-024-09732-y","DOIUrl":null,"url":null,"abstract":"<p>This study compares the accuracy of dosimetry calculations using the Monte Carlo (MC) method and the MIRD method for <sup>99m</sup>Tc-HMPAO, <sup>99m</sup>Tc-DMSA, and <sup>99m</sup>Tc-sulfur colloid administered to an adult female patient undergoing SPECT imaging. Comparing the two methods, the dose estimation differences between MC and MIRD methods were found to be 11.57%, 1.70%, and 30.04% for <sup>99m</sup>Tc-HMPAO, <sup>99m</sup>Tc-DMSA, and <sup>99m</sup>Tc-sulfur colloid, respectively. In conclusion, this study emphasizes the importance of accurate dosimetry in nuclear medicine. The MC method perform better than the MIRD method in predicting absorbed doses, making it a valuable tool for optimizing radiation therapies and improving patient outcomes.</p>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Calculation of the absorbed dose to 99mTc-HMPAO, 99mTc-DMSA, and 99mTc-sulfur colloid injected patients by using Monte Carlo and MIRD methods\",\"authors\":\"Farzane Mohajeri, Ahad Ollah Ezzati\",\"doi\":\"10.1007/s10967-024-09732-y\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>This study compares the accuracy of dosimetry calculations using the Monte Carlo (MC) method and the MIRD method for <sup>99m</sup>Tc-HMPAO, <sup>99m</sup>Tc-DMSA, and <sup>99m</sup>Tc-sulfur colloid administered to an adult female patient undergoing SPECT imaging. Comparing the two methods, the dose estimation differences between MC and MIRD methods were found to be 11.57%, 1.70%, and 30.04% for <sup>99m</sup>Tc-HMPAO, <sup>99m</sup>Tc-DMSA, and <sup>99m</sup>Tc-sulfur colloid, respectively. In conclusion, this study emphasizes the importance of accurate dosimetry in nuclear medicine. The MC method perform better than the MIRD method in predicting absorbed doses, making it a valuable tool for optimizing radiation therapies and improving patient outcomes.</p>\",\"PeriodicalId\":661,\"journal\":{\"name\":\"Journal of Radioanalytical and Nuclear Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2024-09-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Radioanalytical and Nuclear Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1007/s10967-024-09732-y\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Radioanalytical and Nuclear Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s10967-024-09732-y","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Calculation of the absorbed dose to 99mTc-HMPAO, 99mTc-DMSA, and 99mTc-sulfur colloid injected patients by using Monte Carlo and MIRD methods
This study compares the accuracy of dosimetry calculations using the Monte Carlo (MC) method and the MIRD method for 99mTc-HMPAO, 99mTc-DMSA, and 99mTc-sulfur colloid administered to an adult female patient undergoing SPECT imaging. Comparing the two methods, the dose estimation differences between MC and MIRD methods were found to be 11.57%, 1.70%, and 30.04% for 99mTc-HMPAO, 99mTc-DMSA, and 99mTc-sulfur colloid, respectively. In conclusion, this study emphasizes the importance of accurate dosimetry in nuclear medicine. The MC method perform better than the MIRD method in predicting absorbed doses, making it a valuable tool for optimizing radiation therapies and improving patient outcomes.
期刊介绍：
An international periodical publishing original papers, letters, review papers and short communications on nuclear chemistry. The subjects covered include: Nuclear chemistry, Radiochemistry, Radiation chemistry, Radiobiological chemistry, Environmental radiochemistry, Production and control of radioisotopes and labelled compounds, Nuclear power plant chemistry, Nuclear fuel chemistry, Radioanalytical chemistry, Radiation detection and measurement, Nuclear instrumentation and automation, etc.
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