酶解杂环中间体,制备具有生物活性的化合物

Anastasy Kolodiazhna, Dmitry Prysiazhnuk, Oleg Kolodiazhnyi
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摘要

在有机介质中,通过酶促动力学控制脱嵌,将一些具有生物活性的杂环合成物分解成对映体。高对映体选择性(>98...
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Enzymatic resolution of heterocyclic intermediates for biologically active compound preparation
A number of heterocyclic synthons of biologically active compounds were resolved into enantiomers by enzymatic kinetically controlled deracemization in organic media. High enantioselectivities (>98...
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