{"title":"用于自动细胞划分的开源基础设施","authors":"Aaron Rock Menezes, Bharath Ramsundar","doi":"arxiv-2409.08163","DOIUrl":null,"url":null,"abstract":"Automated cell segmentation is crucial for various biological and medical\napplications, facilitating tasks like cell counting, morphology analysis, and\ndrug discovery. However, manual segmentation is time-consuming and prone to\nsubjectivity, necessitating robust automated methods. This paper presents\nopen-source infrastructure, utilizing the UNet model, a deep-learning\narchitecture noted for its effectiveness in image segmentation tasks. This\nimplementation is integrated into the open-source DeepChem package, enhancing\naccessibility and usability for researchers and practitioners. The resulting\ntool offers a convenient and user-friendly interface, reducing the barrier to\nentry for cell segmentation while maintaining high accuracy. Additionally, we\nbenchmark this model against various datasets, demonstrating its robustness and\nversatility across different imaging conditions and cell types.","PeriodicalId":501266,"journal":{"name":"arXiv - QuanBio - Quantitative Methods","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Open Source Infrastructure for Automatic Cell Segmentation\",\"authors\":\"Aaron Rock Menezes, Bharath Ramsundar\",\"doi\":\"arxiv-2409.08163\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Automated cell segmentation is crucial for various biological and medical\\napplications, facilitating tasks like cell counting, morphology analysis, and\\ndrug discovery. However, manual segmentation is time-consuming and prone to\\nsubjectivity, necessitating robust automated methods. This paper presents\\nopen-source infrastructure, utilizing the UNet model, a deep-learning\\narchitecture noted for its effectiveness in image segmentation tasks. This\\nimplementation is integrated into the open-source DeepChem package, enhancing\\naccessibility and usability for researchers and practitioners. The resulting\\ntool offers a convenient and user-friendly interface, reducing the barrier to\\nentry for cell segmentation while maintaining high accuracy. Additionally, we\\nbenchmark this model against various datasets, demonstrating its robustness and\\nversatility across different imaging conditions and cell types.\",\"PeriodicalId\":501266,\"journal\":{\"name\":\"arXiv - QuanBio - Quantitative Methods\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"arXiv - QuanBio - Quantitative Methods\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/arxiv-2409.08163\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"arXiv - QuanBio - Quantitative Methods","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/arxiv-2409.08163","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Open Source Infrastructure for Automatic Cell Segmentation
Automated cell segmentation is crucial for various biological and medical
applications, facilitating tasks like cell counting, morphology analysis, and
drug discovery. However, manual segmentation is time-consuming and prone to
subjectivity, necessitating robust automated methods. This paper presents
open-source infrastructure, utilizing the UNet model, a deep-learning
architecture noted for its effectiveness in image segmentation tasks. This
implementation is integrated into the open-source DeepChem package, enhancing
accessibility and usability for researchers and practitioners. The resulting
tool offers a convenient and user-friendly interface, reducing the barrier to
entry for cell segmentation while maintaining high accuracy. Additionally, we
benchmark this model against various datasets, demonstrating its robustness and
versatility across different imaging conditions and cell types.