便携式多导睡眠图仪(Somnocheck micro CARDIO®)为有阻塞性睡眠呼吸暂停风险的精神病患者提供准确的诊断信息:一项观察性队列研究

IF 3.4 2区 医学 Q2 PSYCHIATRY BMC Psychiatry Pub Date : 2024-09-10 DOI:10.1186/s12888-024-06049-8
Maximilian Bailer, Eva M. Stein, Maximilian I. Sprügel, Stefan Mestermann, Philipp Spitzer, Janine Utz, Sabine Zirlik, Florian S. Fuchs, Johannes Kornhuber
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引用次数: 0

摘要

阻塞性睡眠呼吸暂停(OSA)的症状与精神疾病的症状严重重叠,因此在精神科环境中准确诊断 OSA 具有挑战性。对精神病患者进行 OSA 诊断至关重要,因为未经治疗的 OSA 会加重精神病症状、降低治疗效果并损害整体生活质量。本研究旨在通过比较 Somnocheck micro CARDIO® (SCm) 便携式心肺功能测谎仪与黄金标准多导睡眠图 (PSG) ,确定在真实的临床环境中为精神病患者提供的便捷程序的诊断准确性。这项观察性队列研究纳入了 2016 年 6 月 1 日至 2022 年 12 月 31 日期间在一家三级医疗中心住院的连续精神病患者,这些患者根据 STOP-Bang 问卷筛查结果属于 OSA 中高风险人群。呼吸暂停-高通气指数(AHI)、呼吸暂停指数(AI)、氧饱和度指数(ODI)和最低血氧饱和度依次由 SCm 和 PSG 测量。共分析了 57 名患者(中位年龄 62.0 [四分位距(IQR),51.5-72.5] 岁;男性 34 [59.6%])。关于 AHI,SCm 和 PSG 之间没有发现明显差异(PSG 测量的 AHI 中位数为 16.6 [IQR,6.2-26.7],而 SCm 测量的 AHI 中位数为 14.9 [IQR,10.0-22.8];p = 0.812;r = 0.71)。AI、ODI 和最低血氧饱和度在 SCm 和 PSG 之间存在显著差异。使用优化的临界值(任何 OSA:AHISCm ≥ 9.25),SCm 诊断 OSA 的灵敏度高(0.894),特异性高(0.800),接收器工作特征曲线下的面积为 0.877。本研究发现,SCm 便携式设备能准确识别患有 OSA 的精神病患者。与金标准多导睡眠图相比,SCm 的 AHI 测量具有可靠的诊断性能。这些研究结果支持将多导睡眠图测量纳入精神病患者的常规睡眠评估中。对这一人群进行早期、准确的 OSA 诊断可显著改善对睡眠障碍和精神疾病的管理,从而提高这些患者的整体治疗效果和生活质量。
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Portable polygraphic device (Somnocheck micro CARDIO®) provides accurate diagnostic information in psychiatric patients at risk for obstructive sleep apnoea: an observational cohort study
Symptoms of obstructive sleep apnoea (OSA) overlap significantly with those of psychiatric disorders, making accurate diagnosis of OSA challenging within psychiatric settings. Diagnosing OSA in psychiatric patients is crucial because untreated OSA can exacerbate psychiatric symptoms, reduce treatment efficacy, and impair overall quality of life. This study aimed to determine the diagnostic accuracy of a readily accessible procedure for psychiatric patients in a real-world clinical setting by comparing the Somnocheck micro CARDIO® (SCm) portable cardiorespiratory polygraphy device with the gold standard polysomnography (PSG). This observational cohort study included consecutive psychiatric patients at intermediate to high risk for OSA based on screening with the STOP-Bang questionnaire, admitted to a single tertiary care centre between June 1, 2016 and December 31, 2022. The Apnoea-Hypopnoea-Index (AHI), Apnoea-Index (AI), Oxygen-Desaturation-Index (ODI), and minimum oxygen saturation were measured sequentially by SCm and PSG. A total of 57 patients were analysed (median age 62.0 [Interquartile Range (IQR), 51.5–72.5] years; 34 [59.6%] men). Regarding AHI, no significant differences (AHI measured by PSG, median, 16.6 [IQR, 6.2–26.7] vs. AHI measured by SCm, median, 14.9 [IQR, 10.0-22.8]; p = 0.812; r = 0.71) were found between SCm and PSG. AI, ODI and minimum oxygen saturation differed significantly between SCm and PSG. Using optimised cut-off values (any OSA: AHISCm ≥ 9.25), SCm showed high sensitivity (0.894) and high specificity (0.800) for the diagnosis of OSA, with an area under the receiver operating characteristic curve of 0.877. This study found that the SCm portable device was accurate in identifying psychiatric patients with OSA. AHI measurement by SCm provided reliable diagnostic performance in comparison with the gold standard polysomnography. These findings support the integration of polygraphic measurements into the routine sleep assessment of psychiatric patients. Early and accurate diagnosis of OSA in this population can significantly improve the management of both sleep disorders and psychiatric conditions, potentially enhancing overall treatment outcomes and quality of life for these patients.
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来源期刊
BMC Psychiatry
BMC Psychiatry 医学-精神病学
CiteScore
5.90
自引率
4.50%
发文量
716
审稿时长
3-6 weeks
期刊介绍: BMC Psychiatry is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of psychiatric disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
期刊最新文献
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