急性主动脉综合征

The BMJ Pub Date : 2024-09-17 DOI:10.1136/bmj-2024-080870
Steve Goodacre, Valerie Lechene, Graham Cooper, Sarah Wilson, Jim Zhong
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摘要

### 您需要了解的信息 一位 50 多岁的健康女性突然感到撕裂般的疼痛,就像一道闪电从颈部窜到胸部,再放射到背部,疼痛一波一波地袭来,严重程度在随后的几个小时内时轻时重。有时她还能说话,甚至能走路,但她感觉自己的意识水平大多下降,呼吸困难。她感到头晕和恶心。她的母亲在三年前的一次 A 型主动脉夹层中幸存了下来,享年 77 岁。救护车被叫来,90 分钟后到达。医护人员根据她的症状初步诊断为主动脉夹层。这名妇女被口服吗啡并送往医院,45 分钟后到达医院。在急诊科,她被初步诊断为恐慌症发作,并接受了保守治疗,直到几小时后再次评估时才触发计算机断层扫描血管造影术,结果显示主动脉夹层。急性主动脉综合征(AAS)是一种危及生命的疾病,胸主动脉撕裂可导致主动脉破裂和死亡。它包括三种情况:急性主动脉夹层、壁内血肿和穿透性溃疡1,通常分为斯坦福A型(涉及升主动脉)和B型(不涉及升主动脉)。
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Acute aortic syndrome
### What you need to know A healthy woman in her mid 50s experiences sudden, tearing pain, like a lightning bolt from her neck to her chest, radiating to her back, coming in waves, with severity fluctuating over subsequent hours. At times she is able to talk and even walk, but she feels that her consciousness level is mostly reduced, and she has difficulty breathing. She feels dizzy and nauseous. Her mother survived a type A aortic dissection, three years previously, at the age of 77. An ambulance is called and arrives 90 minutes later. A paramedic makes a tentative diagnosis of aortic dissection based on the presenting features. The woman is given oral morphine and transported to hospital, arriving 45 minutes later. In the emergency department she receives an initial diagnosis of panic attack and is managed conservatively, until reassessment some hours later triggers computed tomography angiography, which shows an aortic dissection. Acute aortic syndrome (AAS) is a life threatening condition where a tear in the thoracic aorta can lead to rupture of the aorta and death. It encompasses three conditions: acute aortic dissection; intra-mural haematoma; and penetrating ulcer,1 and is commonly classified into Stanford type A (involving the ascending aorta) and type B (sparing the …
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