{"title":"在无催化剂条件下一步法连续合成融合和非融合多取代二氢吡啶衍生物","authors":"Fatemeh Asilpour, Dariush Saberi, Alireza Hasaninejad","doi":"10.1016/j.tet.2024.134279","DOIUrl":null,"url":null,"abstract":"<div><p>A one-pot, sequential, three-component procedure is reported for the synthesis of poly-substituted dihydropyridines <em>via</em> the condensation reaction of diamines or aminophenoles, 1,1-bismethylmethio-2-nitroethylene and <em>α</em>,<em>β</em>-unsaturated aromatic ketones in acetonitrile under reflux conditions. A range of fused and non-fused poly-substituted dihydropyridines were prepared in good to high yields with short reaction times.</p></div>","PeriodicalId":437,"journal":{"name":"Tetrahedron","volume":"167 ","pages":"Article 134279"},"PeriodicalIF":2.1000,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"One-pot sequential synthesis of fused and non-fused poly-substituted dihydropyridine derivatives under catalyst-free conditions\",\"authors\":\"Fatemeh Asilpour, Dariush Saberi, Alireza Hasaninejad\",\"doi\":\"10.1016/j.tet.2024.134279\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>A one-pot, sequential, three-component procedure is reported for the synthesis of poly-substituted dihydropyridines <em>via</em> the condensation reaction of diamines or aminophenoles, 1,1-bismethylmethio-2-nitroethylene and <em>α</em>,<em>β</em>-unsaturated aromatic ketones in acetonitrile under reflux conditions. A range of fused and non-fused poly-substituted dihydropyridines were prepared in good to high yields with short reaction times.</p></div>\",\"PeriodicalId\":437,\"journal\":{\"name\":\"Tetrahedron\",\"volume\":\"167 \",\"pages\":\"Article 134279\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2024-09-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tetrahedron\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0040402024004605\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tetrahedron","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0040402024004605","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
One-pot sequential synthesis of fused and non-fused poly-substituted dihydropyridine derivatives under catalyst-free conditions
A one-pot, sequential, three-component procedure is reported for the synthesis of poly-substituted dihydropyridines via the condensation reaction of diamines or aminophenoles, 1,1-bismethylmethio-2-nitroethylene and α,β-unsaturated aromatic ketones in acetonitrile under reflux conditions. A range of fused and non-fused poly-substituted dihydropyridines were prepared in good to high yields with short reaction times.
期刊介绍：
Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry.
Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters.
Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
