外源性褪黑激素对杂交肉牛断奶后免疫反应和生长性能的影响

IF 1.4 Q3 AGRICULTURE, DAIRY & ANIMAL SCIENCE Applied Animal Science Pub Date : 2024-09-16 DOI:10.15232/aas.2024-02555
Allie E. Martin, Vinicius S. Machado, Ryan J. Rathmann, Whitney L. Crossland
{"title":"外源性褪黑激素对杂交肉牛断奶后免疫反应和生长性能的影响","authors":"Allie E. Martin,&nbsp;Vinicius S. Machado,&nbsp;Ryan J. Rathmann,&nbsp;Whitney L. Crossland","doi":"10.15232/aas.2024-02555","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>Our objective was to evaluate the effects of exogenous melatonin on the immune response and growth performance of beef calves during a vaccination series at weaning.</p></div><div><h3>Materials and Methods</h3><p>Crossbred beef calves (n = 48, initial BW = 176 ± 21.7 kg) were enrolled in a completely randomized design with a 2 × 2 factorial arrangement of treatments: vaccinated with 0.5 mg of ovalbumin (d 0 and 21) or not, and a 24-mg injection of melatonin (d 0 and 21) or not. Treatments were placebo injections only (CON), vaccination only (VAC), melatonin only (MEL), and both melatonin and vaccination (MVAC). Calves were weaned on d 0 and fed for 63 d. Calf BW and blood samples were collected on d 0, 2, 4, 8, 21, 42, and 63.</p></div><div><h3>Results and Discussion</h3><p>On d 8, MEL-treated calves had a greater percentage of cells performing oxidative burst and a greater percentage of cells performing phagocytosis, and these were at a greater intensity. On d 21, MEL-treated calves also had greater burst intensity than other treatments. Melatonin alone may bolster the innate immune response. Anti-ovalbumin IgG response was different on d 63, where MVAC calves had greater circulating anti-ovalbumin IgG compared with VAC calves. Calves who received VAC treatment had greater DMI than calves who received MVAC, and MVAC-treated calves tended to have a greater G:F than VAC calves. The administration of melatonin at the time of vaccination resulted in greater feed conversion and greater IgG than VAC alone.</p></div><div><h3>Implications and Applications</h3><p>Melatonin may bolster the immune response of calves at weaning and improve feed conversion, incentivizing its adoption as a management protocol.</p></div>","PeriodicalId":8519,"journal":{"name":"Applied Animal Science","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590286524000922/pdf?md5=37fdb6f979b9dcab830892778a055e43&pid=1-s2.0-S2590286524000922-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Effects of exogenous melatonin on the postweaning immune response and growth performance of crossbred beef calves\",\"authors\":\"Allie E. Martin,&nbsp;Vinicius S. Machado,&nbsp;Ryan J. Rathmann,&nbsp;Whitney L. Crossland\",\"doi\":\"10.15232/aas.2024-02555\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>Our objective was to evaluate the effects of exogenous melatonin on the immune response and growth performance of beef calves during a vaccination series at weaning.</p></div><div><h3>Materials and Methods</h3><p>Crossbred beef calves (n = 48, initial BW = 176 ± 21.7 kg) were enrolled in a completely randomized design with a 2 × 2 factorial arrangement of treatments: vaccinated with 0.5 mg of ovalbumin (d 0 and 21) or not, and a 24-mg injection of melatonin (d 0 and 21) or not. Treatments were placebo injections only (CON), vaccination only (VAC), melatonin only (MEL), and both melatonin and vaccination (MVAC). Calves were weaned on d 0 and fed for 63 d. Calf BW and blood samples were collected on d 0, 2, 4, 8, 21, 42, and 63.</p></div><div><h3>Results and Discussion</h3><p>On d 8, MEL-treated calves had a greater percentage of cells performing oxidative burst and a greater percentage of cells performing phagocytosis, and these were at a greater intensity. On d 21, MEL-treated calves also had greater burst intensity than other treatments. Melatonin alone may bolster the innate immune response. Anti-ovalbumin IgG response was different on d 63, where MVAC calves had greater circulating anti-ovalbumin IgG compared with VAC calves. Calves who received VAC treatment had greater DMI than calves who received MVAC, and MVAC-treated calves tended to have a greater G:F than VAC calves. The administration of melatonin at the time of vaccination resulted in greater feed conversion and greater IgG than VAC alone.</p></div><div><h3>Implications and Applications</h3><p>Melatonin may bolster the immune response of calves at weaning and improve feed conversion, incentivizing its adoption as a management protocol.</p></div>\",\"PeriodicalId\":8519,\"journal\":{\"name\":\"Applied Animal Science\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2024-09-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2590286524000922/pdf?md5=37fdb6f979b9dcab830892778a055e43&pid=1-s2.0-S2590286524000922-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied Animal Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2590286524000922\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"AGRICULTURE, DAIRY & ANIMAL SCIENCE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Animal Science","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2590286524000922","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"AGRICULTURE, DAIRY & ANIMAL SCIENCE","Score":null,"Total":0}
引用次数: 0

摘要

材料与方法杂交肉牛犊牛(n = 48,初始体重 = 176 ± 21.7 kg)被纳入完全随机设计的 2 × 2 处理因子安排:接种 0.5 mg 卵清蛋白(第 0 天和第 21 天)或不接种,以及注射 24 毫克褪黑激素(第 0 天和第 21 天)或不注射。治疗方法包括只注射安慰剂 (CON)、只注射疫苗 (VAC)、只注射褪黑激素 (MEL) 以及同时注射褪黑激素和疫苗 (MVAC)。在第 0、2、4、8、21、42 和 63 天采集犊牛体重和血液样本。 结果与讨论在第 8 天,MEL 处理的犊牛有更大比例的细胞进行氧化爆发,有更大比例的细胞进行吞噬作用,而且这些作用的强度更大。第 21 天,MEL 处理的小牛的细胞猝灭强度也高于其他处理。单独使用褪黑素可能会增强先天性免疫反应。抗白蛋白 IgG 反应在第 63 天有所不同,与 VAC 小牛相比,MVAC 小牛的循环抗白蛋白 IgG 更大。接受 VAC 治疗的犊牛的 DMI 比接受 MVAC 治疗的犊牛大,MVAC 治疗的犊牛的 G:F 往往比 VAC 治疗的犊牛大。意义和应用褪黑素可增强犊牛断奶时的免疫反应,提高饲料转化率,从而鼓励将其作为一种管理方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Effects of exogenous melatonin on the postweaning immune response and growth performance of crossbred beef calves

Objective

Our objective was to evaluate the effects of exogenous melatonin on the immune response and growth performance of beef calves during a vaccination series at weaning.

Materials and Methods

Crossbred beef calves (n = 48, initial BW = 176 ± 21.7 kg) were enrolled in a completely randomized design with a 2 × 2 factorial arrangement of treatments: vaccinated with 0.5 mg of ovalbumin (d 0 and 21) or not, and a 24-mg injection of melatonin (d 0 and 21) or not. Treatments were placebo injections only (CON), vaccination only (VAC), melatonin only (MEL), and both melatonin and vaccination (MVAC). Calves were weaned on d 0 and fed for 63 d. Calf BW and blood samples were collected on d 0, 2, 4, 8, 21, 42, and 63.

Results and Discussion

On d 8, MEL-treated calves had a greater percentage of cells performing oxidative burst and a greater percentage of cells performing phagocytosis, and these were at a greater intensity. On d 21, MEL-treated calves also had greater burst intensity than other treatments. Melatonin alone may bolster the innate immune response. Anti-ovalbumin IgG response was different on d 63, where MVAC calves had greater circulating anti-ovalbumin IgG compared with VAC calves. Calves who received VAC treatment had greater DMI than calves who received MVAC, and MVAC-treated calves tended to have a greater G:F than VAC calves. The administration of melatonin at the time of vaccination resulted in greater feed conversion and greater IgG than VAC alone.

Implications and Applications

Melatonin may bolster the immune response of calves at weaning and improve feed conversion, incentivizing its adoption as a management protocol.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Applied Animal Science
Applied Animal Science AGRICULTURE, DAIRY & ANIMAL SCIENCE-
CiteScore
3.00
自引率
6.70%
发文量
68
期刊最新文献
Table of Contents Editorial Board Call for Submissions Fabrication yields and allometric growth coefficients of carcass components of serially slaughtered implanted or non-implanted beef steers Comparison of a single extended-release implant and a re-implant strategy on performance and carcass characteristics of beef finishing heifers
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1