探索非门禁社区与门禁社区居民牙齿中重金属浓度变化的比较研究

IF 3.4 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Biological Trace Element Research Pub Date : 2024-09-17 DOI:10.1007/s12011-024-04372-5
Bushra Ahmed Karim, Gauhar Mahmood, Salim Sheikh
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引用次数: 0

摘要

人类与重金属的接触日益频繁,对健康造成了极大的威胁。牙本质和珐琅质等牙齿组织因其稳定的性质,为评估长期重金属暴露提供了可靠的生物标志物。本研究旨在探讨居住在印度新德里亚穆纳河(Yamuna River)附近有门禁和无门禁社区的居民牙齿牙本质中重金属浓度的变化情况。实验共招募了 69 名参与者,其中 27 人来自有门禁的社区,42 人来自无门禁的社区。参与者进行了选择性拔牙,之后使用原子吸收分光光度法测量了拔出牙齿牙本质中的重金属浓度。人口统计学数据包括年龄、性别、牙齿类型和饮用水来源。统计分析包括曼-惠特尼检验、斯皮尔曼相关热图和主成分分析(PCA)。与门禁社区相比,非门禁社区居民的重金属平均浓度明显更高(p < 0.005),但镉除外(p = 0.495)。基于饮用水源的分组分析显示,重金属浓度存在显著差异(p < 0.001),表明水质对环境暴露有影响。PCA 分析有助于深入了解重金属变量之间的潜在趋势和相关性。这项研究为了解亚穆纳河附近居民的重金属污染情况提供了有价值的信息,突出了居住环境和饮用水源对重金属暴露的影响。与来自封闭小区的参与者相比,来自非封闭小区的参与者表现出更高的重金属平均浓度,这强调了社会经济因素、城市基础设施和环境管理措施对重金属积累的影响。研究结果突出表明,有必要采取有针对性的干预措施,解决不同人群的重金属暴露问题,提高水质标准,增加安全饮用水的获取途径。
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A Comparative Study to Explore the Variability of Heavy Metal Concentration in the Teeth of Residents of Non-gated Versus Gated Societies

Human populations face increasing exposure to heavy metals, which pose significant health risks. Dental tissues, such as dentin and enamel, provide a reliable biomarker for assessing long-term heavy metal exposure due to their stable nature. This study aims to explore the variability of heavy metal concentrations in the teeth dentine of residents living in gated versus non-gated societies near the Yamuna River around the Jamia Millia Islamia, New Delhi, India. Sixty-nine participants were enrolled, 27 from gated societies and 42 from non-gated societies. Participants underwent elective dental extraction, following which heavy metal concentrations were measured in extracted tooth dentine using atomic absorption spectrophotometry. Demographic data including age, gender, tooth types, and drinking water sources were recorded. Statistical analysis included Mann–Whitney’s test, Spearman correlation heatmap, and principal component analysis (PCA). Residents of non-gated societies exhibited significantly (< 0.005) higher mean concentrations of heavy metals compared to gated societies except for cadmium (p = 0.495). Subgroup analysis based on drinking water sources revealed significant (< 0.001) variations in heavy metal concentrations, suggesting the influence of water quality on environmental exposure. PCA provided insights into underlying trends and correlations among heavy metal variables. This study provides valuable insights into heavy metal contamination among residents living near the Yamuna River, highlighting disparities in exposure based on residential environment and drinking water sources. Participants from non-gated societies exhibited higher mean concentrations of heavy metals compared to those from gated societies, emphasizing the influence of socio-economic factors, urban infrastructure and environmental management practices on heavy metal accumulation. The study’s findings underscore the need for targeted interventions to address heavy metal exposure across diverse population groups, improve water quality standards, and enhance access to safe drinking water.

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来源期刊
Biological Trace Element Research
Biological Trace Element Research 生物-内分泌学与代谢
CiteScore
8.70
自引率
10.30%
发文量
459
审稿时长
2 months
期刊介绍: Biological Trace Element Research provides a much-needed central forum for the emergent, interdisciplinary field of research on the biological, environmental, and biomedical roles of trace elements. Rather than confine itself to biochemistry, the journal emphasizes the integrative aspects of trace metal research in all appropriate fields, publishing human and animal nutritional studies devoted to the fundamental chemistry and biochemistry at issue as well as to the elucidation of the relevant aspects of preventive medicine, epidemiology, clinical chemistry, agriculture, endocrinology, animal science, pharmacology, microbiology, toxicology, virology, marine biology, sensory physiology, developmental biology, and related fields.
期刊最新文献
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