回归：反义抑制 Bcr-Abl/c-Abl 合成可促进端粒酶活性并上调人类白血病细胞中的坦克酶

IF 3.5 4区生物学 Q1 Biochemistry, Genetics and Molecular Biology FEBS Letters Pub Date : 2024-09-18 DOI:10.1002/1873-3468.15022

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引用次数: 0

摘要

R. Bakalova, H. Ohba, Z. Zhelev, T. Kubo, M. Fujii, M. Ishikawa, Y. Shinohara, and Y. Baba, 'Antisense inhibition of Bcr-Abl/c-Abl synthesis promotes telomerase activity and upregulates tankyrase in human leukemia cells,' FEBS Letters 564, no：73-84, https://doi.org/10.1016/S0014-5793(04)00318-7。上述文章于 2004 年 4 月 9 日在线发表于 Wiley Online Library (wileyonlinelibrary.com)，经作者、期刊主编 Michael Brunner、FEBS 出版社、美国国家先进工业科学技术研究所 (AIST) 和 John Wiley and Sons Ltd.协商，上述文章已被撤回。AIST 随后进行的机构调查显示图 2A K-562 的 Western 印迹中 4 天和 6 天的β-肌动蛋白负载对照之间、图 4A K-562 和 Jurkat 细胞的电泳印迹子印迹之间以及图 6B 的电泳印迹子印迹之间的图像板不适当地重复。图 6A p210 Bcr-Ab 道 Western 印迹中的条带插入。本文（图 2A K562 β-肌动蛋白和图 4B K562 6 天处理条带）与 2003 年发表的一篇较早的文章（由一组代表不同实验条件的重叠作者撰写）中的图片不适当地重复。本文（图 3A2）与 2004 年发表的一篇较早的文章（由代表不同实验条件的一组重叠作者撰写）之间的图像有不恰当的重复和修改。因此，该论文的结论大打折扣，研究所建议撤回该论文。根据机构调查，期刊编辑同意撤稿。

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RETRACTION: Antisense inhibition of Bcr-Abl/c-Abl synthesis promotes telomerase activity and upregulates tankyrase in human leukemia cells

RETRACTION: R. Bakalova, H. Ohba, Z. Zhelev, T. Kubo, M. Fujii, M. Ishikawa, Y. Shinohara, and Y. Baba, ‘Antisense inhibition of Bcr-Abl/c-Abl synthesis promotes telomerase activity and upregulates tankyrase in human leukemia cells,' FEBS Letters 564, no. 1–2 (2004): 73–84, https://doi.org/10.1016/S0014-5793(04)00318-7.

The above article, published online on 9 April 2004 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors; the journal Editor-in-Chief, Michael Brunner; FEBS Press; the National Institute of Advanced Industrial Science and Technology (AIST); and John Wiley and Sons Ltd.

Following publication, concerns were raised by a third-party regarding several figures in the article. The subsequent institutional investigation conducted by the AIST revealed:

Therefore, the conclusions of the paper are substantially compromised and the institute has recommended the paper to be retracted. The editors of the journal agree with the retraction based on the institutional investigation.

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来源期刊

FEBS Letters 生物-生化与分子生物学

CiteScore

7.00

自引率

2.90%

发文量

303

审稿时长

1.0 months

期刊介绍： FEBS Letters is one of the world''s leading journals in molecular biology and is renowned both for its quality of content and speed of production. Bringing together the most important developments in the molecular biosciences, FEBS Letters provides an international forum for Minireviews, Research Letters and Hypotheses that merit urgent publication.