Andrea López-Suárez, Mar Santos-Sebastián, Alicia Hernanz-Lobo, Elena Rincón-López, David Aguilera-Alonso, Jesús Saavedra-Lozano, María Jesús Ruiz Serrano, Ángel Hernández-Bartolomé, Luz María Medrano de Dios, José Luis Jiménez Fuentes, María Luisa Navarro, Marc Tebruegge, Begoña Santiago-García
{"title":"结合小儿肺结核组织损伤和炎症的血浆生物标志物的诊断潜力","authors":"Andrea López-Suárez, Mar Santos-Sebastián, Alicia Hernanz-Lobo, Elena Rincón-López, David Aguilera-Alonso, Jesús Saavedra-Lozano, María Jesús Ruiz Serrano, Ángel Hernández-Bartolomé, Luz María Medrano de Dios, José Luis Jiménez Fuentes, María Luisa Navarro, Marc Tebruegge, Begoña Santiago-García","doi":"10.1016/j.jmii.2024.07.011","DOIUrl":null,"url":null,"abstract":"Immune-based diagnostic tests for tuberculosis (TB) have suboptimal sensitivity in children and cannot differentiate between latent infection (LTBI) and active disease. This study evaluated the diagnostic potential of a broad range of biomarkers of tissue damage and inflammation in unstimulated plasma in children.","PeriodicalId":56117,"journal":{"name":"Journal of Microbiology Immunology and Infection","volume":null,"pages":null},"PeriodicalIF":4.5000,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diagnostic potential of combining plasma biomarkers of tissue damage and inflammation in pediatric TB\",\"authors\":\"Andrea López-Suárez, Mar Santos-Sebastián, Alicia Hernanz-Lobo, Elena Rincón-López, David Aguilera-Alonso, Jesús Saavedra-Lozano, María Jesús Ruiz Serrano, Ángel Hernández-Bartolomé, Luz María Medrano de Dios, José Luis Jiménez Fuentes, María Luisa Navarro, Marc Tebruegge, Begoña Santiago-García\",\"doi\":\"10.1016/j.jmii.2024.07.011\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Immune-based diagnostic tests for tuberculosis (TB) have suboptimal sensitivity in children and cannot differentiate between latent infection (LTBI) and active disease. This study evaluated the diagnostic potential of a broad range of biomarkers of tissue damage and inflammation in unstimulated plasma in children.\",\"PeriodicalId\":56117,\"journal\":{\"name\":\"Journal of Microbiology Immunology and Infection\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.5000,\"publicationDate\":\"2024-09-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Microbiology Immunology and Infection\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.jmii.2024.07.011\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Microbiology Immunology and Infection","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jmii.2024.07.011","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
Diagnostic potential of combining plasma biomarkers of tissue damage and inflammation in pediatric TB
Immune-based diagnostic tests for tuberculosis (TB) have suboptimal sensitivity in children and cannot differentiate between latent infection (LTBI) and active disease. This study evaluated the diagnostic potential of a broad range of biomarkers of tissue damage and inflammation in unstimulated plasma in children.
期刊介绍:
Journal of Microbiology Immunology and Infection is an open access journal, committed to disseminating information on the latest trends and advances in microbiology, immunology, infectious diseases and parasitology. Article types considered include perspectives, review articles, original articles, brief reports and correspondence.
With the aim of promoting effective and accurate scientific information, an expert panel of referees constitutes the backbone of the peer-review process in evaluating the quality and content of manuscripts submitted for publication.