使用生物制剂和 Janus 激酶抑制剂的类风湿性关节炎患者感染肺孢子菌的风险增加

IF 4.5 2区医学 Q2 IMMUNOLOGY Journal of Microbiology Immunology and Infection Pub Date : 2024-09-04 DOI:10.1016/j.jmii.2024.08.013

Ya-Chun Huang, Nan-Yao Lee, Meng-Yu Weng

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引用次数: 0

摘要

风湿病患者中肺孢子虫肺炎（PJ）的发病率正在上升。PJ 定植是传播的蓄水池，并先于 PJ 肺炎的发生。我们旨在阐明类风湿性关节炎（RA）患者在接受生物制剂或 Janus 激酶抑制剂（JAKi）治疗时 PJ 定植的相关性。

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Increased risk of Pneumocystis jirovecii colonization in rheumatoid arthritis patients on biologics and Janus kinase inhibitor

The prevalence of Pneumocystis jirovecii (PJ) pneumonia among rheumatic patients is rising. PJ colonization serves as a reservoir for transmission and precedes the development of PJ pneumonia. We aim to clarify the association of PJ colonization in patients of rheumatoid arthritis (RA) treated with biologics or Janus kinase inhibitors (JAKi).

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来源期刊

Journal of Microbiology Immunology and Infection IMMUNOLOGY-INFECTIOUS DISEASES

CiteScore

15.90

自引率

5.40%

发文量

159

审稿时长

67 days

期刊介绍： Journal of Microbiology Immunology and Infection is an open access journal, committed to disseminating information on the latest trends and advances in microbiology, immunology, infectious diseases and parasitology. Article types considered include perspectives, review articles, original articles, brief reports and correspondence. With the aim of promoting effective and accurate scientific information, an expert panel of referees constitutes the backbone of the peer-review process in evaluating the quality and content of manuscripts submitted for publication.