Manoj Manikrao Gadewar, G. K Prashanth, Srilatha Rao, H. S. Lalithamba, N. P. Bhagya, A. S. Sowmyashree, K. Shwetha, Hemantkumar N. Akolkar
{"title":"利用印度蒿叶提取物优化生物相容性银纳米结构的绿色合成：生物医学应用的一个前景广阔的途径","authors":"Manoj Manikrao Gadewar, G. K Prashanth, Srilatha Rao, H. S. Lalithamba, N. P. Bhagya, A. S. Sowmyashree, K. Shwetha, Hemantkumar N. Akolkar","doi":"10.1007/s11243-024-00608-4","DOIUrl":null,"url":null,"abstract":"<p><i>Artemisia indica,</i> belonging to the family Asteraceae, is renowned for its rich phytoconstituents and traditional medicinal uses. This study aimed to optimize the green synthesis of biocompatible Ag NPs using varying concentrations of <i>A. indica</i> leaf extract and AgNO3. The objectives were to characterize the synthesized NPs and evaluate their potential biomedical applications. The synthesized NPs were characterized using FTIR, XRD, TEM, and Zeta sizer. The results indicated an average particle size of approximately 20 nm and a zeta potential of −23.4 mV, confirming their stability. PXRD analysis demonstrated the crystalline nature of the NPs, while FTIR analysis confirmed the capping of phytoconstituents on the nanoparticle surface. Biocompatibility was assessed using the MTT assay on the L929 cell line, showing 83% cell viability, indicating non-toxicity. Additionally, the green-synthesized NPs exhibited significant antibacterial activity at a concentration of 500 μg/mL, as evidenced by a clear zone of inhibition. This study highlights a rapid, eco-friendly synthesis method for Ag NPs, paving the way for novel biomedical applications.</p><h3 data-test=\"abstract-sub-heading\">Graphical Abstract</h3>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Optimized green synthesis of biocompatible Ag nanostructures using Artemisia Indica leaf extract: a promising avenue for biomedical applications\",\"authors\":\"Manoj Manikrao Gadewar, G. K Prashanth, Srilatha Rao, H. S. Lalithamba, N. P. Bhagya, A. S. Sowmyashree, K. Shwetha, Hemantkumar N. Akolkar\",\"doi\":\"10.1007/s11243-024-00608-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><i>Artemisia indica,</i> belonging to the family Asteraceae, is renowned for its rich phytoconstituents and traditional medicinal uses. This study aimed to optimize the green synthesis of biocompatible Ag NPs using varying concentrations of <i>A. indica</i> leaf extract and AgNO3. The objectives were to characterize the synthesized NPs and evaluate their potential biomedical applications. The synthesized NPs were characterized using FTIR, XRD, TEM, and Zeta sizer. The results indicated an average particle size of approximately 20 nm and a zeta potential of −23.4 mV, confirming their stability. PXRD analysis demonstrated the crystalline nature of the NPs, while FTIR analysis confirmed the capping of phytoconstituents on the nanoparticle surface. Biocompatibility was assessed using the MTT assay on the L929 cell line, showing 83% cell viability, indicating non-toxicity. Additionally, the green-synthesized NPs exhibited significant antibacterial activity at a concentration of 500 μg/mL, as evidenced by a clear zone of inhibition. This study highlights a rapid, eco-friendly synthesis method for Ag NPs, paving the way for novel biomedical applications.</p><h3 data-test=\\\"abstract-sub-heading\\\">Graphical Abstract</h3>\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2024-09-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1007/s11243-024-00608-4\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s11243-024-00608-4","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Optimized green synthesis of biocompatible Ag nanostructures using Artemisia Indica leaf extract: a promising avenue for biomedical applications
Artemisia indica, belonging to the family Asteraceae, is renowned for its rich phytoconstituents and traditional medicinal uses. This study aimed to optimize the green synthesis of biocompatible Ag NPs using varying concentrations of A. indica leaf extract and AgNO3. The objectives were to characterize the synthesized NPs and evaluate their potential biomedical applications. The synthesized NPs were characterized using FTIR, XRD, TEM, and Zeta sizer. The results indicated an average particle size of approximately 20 nm and a zeta potential of −23.4 mV, confirming their stability. PXRD analysis demonstrated the crystalline nature of the NPs, while FTIR analysis confirmed the capping of phytoconstituents on the nanoparticle surface. Biocompatibility was assessed using the MTT assay on the L929 cell line, showing 83% cell viability, indicating non-toxicity. Additionally, the green-synthesized NPs exhibited significant antibacterial activity at a concentration of 500 μg/mL, as evidenced by a clear zone of inhibition. This study highlights a rapid, eco-friendly synthesis method for Ag NPs, paving the way for novel biomedical applications.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
