Madeleine L. Giddings, Jacob P. Auringer, Nathan F. Meier, Elizabeth C. Lefferts, Chong Wang, Lindsay Kane‐Barnese
{"title":"脱水对年轻健康成年人中心血压的影响","authors":"Madeleine L. Giddings, Jacob P. Auringer, Nathan F. Meier, Elizabeth C. Lefferts, Chong Wang, Lindsay Kane‐Barnese","doi":"10.1111/cpf.12902","DOIUrl":null,"url":null,"abstract":"PurposeBrachial blood pressure (BP) is the current gold standard for BP assessment; however, measures of pulse wave velocity (PWV) and central blood pressure (CBP) may contribute uniquely to assessment of cardiovascular health status. As of yet, standards for assessment of CBP and PWV have not addressed the impact of hydration status on proper measurement. To understand the impact of hydration, PWV and CBP should be measured in a euhydrated and hypohydrated state.MethodsForty‐three young, healthy participants (21 ± 2 years) completed a dehydration protocol utilizing moderate aerobic activity until they lost 1%–2% of their body weight. PWV and CBP were measured before and following the dehydration protocol. Linear regression was utilized to assess change in hydration status and change in PWV and CBP.ResultsNo significant relationships were observed between the change in hydration status (% body weight lost) and PWV (<jats:italic>β</jats:italic> = 0.05, <jats:italic>p</jats:italic> = 0.78) or central diastolic BP (<jats:italic>β</jats:italic> = −3.8, <jats:italic>p</jats:italic> = 0.10), however, a significant relationship was observed with central systolic BP (<jats:italic>β</jats:italic> = −5.0, <jats:italic>p</jats:italic> = 0.03).DiscussionIn conclusion, the assessment of hydration status before measurement of CBP or PWV may not be necessary in young, healthy individuals.","PeriodicalId":10504,"journal":{"name":"Clinical Physiology and Functional Imaging","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"‘Effects of dehydration on central blood pressure in young healthy adults’\",\"authors\":\"Madeleine L. Giddings, Jacob P. Auringer, Nathan F. Meier, Elizabeth C. Lefferts, Chong Wang, Lindsay Kane‐Barnese\",\"doi\":\"10.1111/cpf.12902\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"PurposeBrachial blood pressure (BP) is the current gold standard for BP assessment; however, measures of pulse wave velocity (PWV) and central blood pressure (CBP) may contribute uniquely to assessment of cardiovascular health status. As of yet, standards for assessment of CBP and PWV have not addressed the impact of hydration status on proper measurement. To understand the impact of hydration, PWV and CBP should be measured in a euhydrated and hypohydrated state.MethodsForty‐three young, healthy participants (21 ± 2 years) completed a dehydration protocol utilizing moderate aerobic activity until they lost 1%–2% of their body weight. PWV and CBP were measured before and following the dehydration protocol. Linear regression was utilized to assess change in hydration status and change in PWV and CBP.ResultsNo significant relationships were observed between the change in hydration status (% body weight lost) and PWV (<jats:italic>β</jats:italic> = 0.05, <jats:italic>p</jats:italic> = 0.78) or central diastolic BP (<jats:italic>β</jats:italic> = −3.8, <jats:italic>p</jats:italic> = 0.10), however, a significant relationship was observed with central systolic BP (<jats:italic>β</jats:italic> = −5.0, <jats:italic>p</jats:italic> = 0.03).DiscussionIn conclusion, the assessment of hydration status before measurement of CBP or PWV may not be necessary in young, healthy individuals.\",\"PeriodicalId\":10504,\"journal\":{\"name\":\"Clinical Physiology and Functional Imaging\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-09-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Physiology and Functional Imaging\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/cpf.12902\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHYSIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Physiology and Functional Imaging","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/cpf.12902","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
‘Effects of dehydration on central blood pressure in young healthy adults’
PurposeBrachial blood pressure (BP) is the current gold standard for BP assessment; however, measures of pulse wave velocity (PWV) and central blood pressure (CBP) may contribute uniquely to assessment of cardiovascular health status. As of yet, standards for assessment of CBP and PWV have not addressed the impact of hydration status on proper measurement. To understand the impact of hydration, PWV and CBP should be measured in a euhydrated and hypohydrated state.MethodsForty‐three young, healthy participants (21 ± 2 years) completed a dehydration protocol utilizing moderate aerobic activity until they lost 1%–2% of their body weight. PWV and CBP were measured before and following the dehydration protocol. Linear regression was utilized to assess change in hydration status and change in PWV and CBP.ResultsNo significant relationships were observed between the change in hydration status (% body weight lost) and PWV (β = 0.05, p = 0.78) or central diastolic BP (β = −3.8, p = 0.10), however, a significant relationship was observed with central systolic BP (β = −5.0, p = 0.03).DiscussionIn conclusion, the assessment of hydration status before measurement of CBP or PWV may not be necessary in young, healthy individuals.
期刊介绍:
Clinical Physiology and Functional Imaging publishes reports on clinical and experimental research pertinent to human physiology in health and disease. The scope of the Journal is very broad, covering all aspects of the regulatory system in the cardiovascular, renal and pulmonary systems with special emphasis on methodological aspects. The focus for the journal is, however, work that has potential clinical relevance. The Journal also features review articles on recent front-line research within these fields of interest.
Covered by the major abstracting services including Current Contents and Science Citation Index, Clinical Physiology and Functional Imaging plays an important role in providing effective and productive communication among clinical physiologists world-wide.