用于生物应用的具有形态结构的自组装多肽

IF 5.5 2区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Biomacromolecules Pub Date : 2024-09-19 DOI:10.1021/acs.biomac.4c01179
Yu Wang, Yusi Liao, Ying-Jin Zhang, Xiu-Hai Wu, Zeng-Ying Qiao, Hao Wang
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引用次数: 0

摘要

肽材料,如自组装肽材料,是非常重要的生物材料。在多种相互作用力的驱动下,多肽分子可以自组装成各种不同性质和功能的宏观形态。近年来,自组装多肽的研究从实验室设计到临床应用都取得了长足的进步。本综述主要介绍自组装肽形成的不同形态,包括纳米颗粒、纳米微粒、纳米管、纳米纤维等。本文还讨论了形态转化的机制和应用,并展望了自组装纳米材料的未来发展方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Self-Assembled Peptide with Morphological Structure for Bioapplication
Peptide materials, such as self-assembled peptide materials, are very important biomaterials. Driven by multiple interaction forces, peptide molecules can self-assemble into a variety of different macroscopic forms with different properties and functions. In recent years, the research on self-assembled peptides has made great progress from laboratory design to clinical application. This review focuses on the different morphologies, including nanoparticles, nanovesicles, nanotubes, nanofibers, and others, formed by self-assembled peptide. The mechanisms and applications of the morphology transformation are also discussed in this paper, and the future direction of self-assembled nanomaterials is envisioned.
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来源期刊
Biomacromolecules
Biomacromolecules 化学-高分子科学
CiteScore
10.60
自引率
4.80%
发文量
417
审稿时长
1.6 months
期刊介绍: Biomacromolecules is a leading forum for the dissemination of cutting-edge research at the interface of polymer science and biology. Submissions to Biomacromolecules should contain strong elements of innovation in terms of macromolecular design, synthesis and characterization, or in the application of polymer materials to biology and medicine. Topics covered by Biomacromolecules include, but are not exclusively limited to: sustainable polymers, polymers based on natural and renewable resources, degradable polymers, polymer conjugates, polymeric drugs, polymers in biocatalysis, biomacromolecular assembly, biomimetic polymers, polymer-biomineral hybrids, biomimetic-polymer processing, polymer recycling, bioactive polymer surfaces, original polymer design for biomedical applications such as immunotherapy, drug delivery, gene delivery, antimicrobial applications, diagnostic imaging and biosensing, polymers in tissue engineering and regenerative medicine, polymeric scaffolds and hydrogels for cell culture and delivery.
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