Guilherme P. Oliveira, Lucas V. de Faria, Natalia M. Caldas, Amanda G. Batista, Suéllen F. L. do Nascimento, Murillo N. T. Silva, Fernanda N. Feiteira, Edson Nossol, Diego P. Rocha, Felipe S. Semaan, Wagner F. Pacheco, Rafael M. Dornellas
{"title":"实验室制造的碳和氧化铝基复合传感器可轻松实现对临床和环境样品中多巴胺的无酶灵敏安培检测","authors":"Guilherme P. Oliveira, Lucas V. de Faria, Natalia M. Caldas, Amanda G. Batista, Suéllen F. L. do Nascimento, Murillo N. T. Silva, Fernanda N. Feiteira, Edson Nossol, Diego P. Rocha, Felipe S. Semaan, Wagner F. Pacheco, Rafael M. Dornellas","doi":"10.1007/s10008-024-06079-y","DOIUrl":null,"url":null,"abstract":"<p>Developing new sensors presenting low-cost, portability, and disposability features is of paramount in the electrochemical field. Thus, this work proposes the fabrication of lab-made composite electrodes using acrylonitrile butadiene styrene, graphite, and aluminum oxide. In this investigation, the amount of aluminum oxide (0 to 12.25 w/w) was carefully optimized, and its impact on the electrochemical performance of the electrode was observed using the ferri-ferro redox probe and dopamine (DOP) as a proof of concept. This innovative electrode was characterized by spectroscopy, morphological, elemental, and electrochemical techniques. Using the alumina-loaded electrode, significantly improved cyclic voltammetric responses regarding peak currents and peak-to-peak separation were obtained for both evaluated species. This sensor was integrated into the batch injection analysis system for amperometric monitoring of DOP in synthetic biological fluids (saliva and urine) and tap water. The developed method showed a wide linear range (10 to 1000 µmol L<sup>−1</sup>), a low detection limit (2.6 µmol L<sup>−1</sup>), and a high analytical frequency (182 analyses per hour). Furthermore, it was precise (RSD < 5%), accurate (recoveries between 90.5 and 107.3%), and selective. Therefore, it can be considered a low-cost alternative analytical tool for electrochemical sensing of DOP in samples of clinical and environmental interest.</p>","PeriodicalId":665,"journal":{"name":"Journal of Solid State Electrochemistry","volume":"106 1","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effortless lab-manufactured carbon and alumina-based composite sensors for enzymeless sensitive amperometric detection of dopamine in clinical and environmental samples\",\"authors\":\"Guilherme P. Oliveira, Lucas V. de Faria, Natalia M. Caldas, Amanda G. Batista, Suéllen F. L. do Nascimento, Murillo N. T. Silva, Fernanda N. Feiteira, Edson Nossol, Diego P. Rocha, Felipe S. Semaan, Wagner F. Pacheco, Rafael M. Dornellas\",\"doi\":\"10.1007/s10008-024-06079-y\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Developing new sensors presenting low-cost, portability, and disposability features is of paramount in the electrochemical field. Thus, this work proposes the fabrication of lab-made composite electrodes using acrylonitrile butadiene styrene, graphite, and aluminum oxide. In this investigation, the amount of aluminum oxide (0 to 12.25 w/w) was carefully optimized, and its impact on the electrochemical performance of the electrode was observed using the ferri-ferro redox probe and dopamine (DOP) as a proof of concept. This innovative electrode was characterized by spectroscopy, morphological, elemental, and electrochemical techniques. Using the alumina-loaded electrode, significantly improved cyclic voltammetric responses regarding peak currents and peak-to-peak separation were obtained for both evaluated species. This sensor was integrated into the batch injection analysis system for amperometric monitoring of DOP in synthetic biological fluids (saliva and urine) and tap water. The developed method showed a wide linear range (10 to 1000 µmol L<sup>−1</sup>), a low detection limit (2.6 µmol L<sup>−1</sup>), and a high analytical frequency (182 analyses per hour). Furthermore, it was precise (RSD < 5%), accurate (recoveries between 90.5 and 107.3%), and selective. 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Effortless lab-manufactured carbon and alumina-based composite sensors for enzymeless sensitive amperometric detection of dopamine in clinical and environmental samples
Developing new sensors presenting low-cost, portability, and disposability features is of paramount in the electrochemical field. Thus, this work proposes the fabrication of lab-made composite electrodes using acrylonitrile butadiene styrene, graphite, and aluminum oxide. In this investigation, the amount of aluminum oxide (0 to 12.25 w/w) was carefully optimized, and its impact on the electrochemical performance of the electrode was observed using the ferri-ferro redox probe and dopamine (DOP) as a proof of concept. This innovative electrode was characterized by spectroscopy, morphological, elemental, and electrochemical techniques. Using the alumina-loaded electrode, significantly improved cyclic voltammetric responses regarding peak currents and peak-to-peak separation were obtained for both evaluated species. This sensor was integrated into the batch injection analysis system for amperometric monitoring of DOP in synthetic biological fluids (saliva and urine) and tap water. The developed method showed a wide linear range (10 to 1000 µmol L−1), a low detection limit (2.6 µmol L−1), and a high analytical frequency (182 analyses per hour). Furthermore, it was precise (RSD < 5%), accurate (recoveries between 90.5 and 107.3%), and selective. Therefore, it can be considered a low-cost alternative analytical tool for electrochemical sensing of DOP in samples of clinical and environmental interest.
期刊介绍:
The Journal of Solid State Electrochemistry is devoted to all aspects of solid-state chemistry and solid-state physics in electrochemistry.
The Journal of Solid State Electrochemistry publishes papers on all aspects of electrochemistry of solid compounds, including experimental and theoretical, basic and applied work. It equally publishes papers on the thermodynamics and kinetics of electrochemical reactions if at least one actively participating phase is solid. Also of interest are articles on the transport of ions and electrons in solids whenever these processes are relevant to electrochemical reactions and on the use of solid-state electrochemical reactions in the analysis of solids and their surfaces.
The journal covers solid-state electrochemistry and focusses on the following fields: mechanisms of solid-state electrochemical reactions, semiconductor electrochemistry, electrochemical batteries, accumulators and fuel cells, electrochemical mineral leaching, galvanic metal plating, electrochemical potential memory devices, solid-state electrochemical sensors, ion and electron transport in solid materials and polymers, electrocatalysis, photoelectrochemistry, corrosion of solid materials, solid-state electroanalysis, electrochemical machining of materials, electrochromism and electrochromic devices, new electrochemical solid-state synthesis.
The Journal of Solid State Electrochemistry makes the professional in research and industry aware of this swift progress and its importance for future developments and success in the above-mentioned fields.