巩固基础:评估子宫韧带完整性在子宫脱垂及其他疾病中的作用。

IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Archives of Gynecology and Obstetrics Pub Date : 2024-09-20 DOI:10.1007/s00404-024-07732-7
Giovanni Pecorella, Radmila Sparic, Andrea Morciano, Ivana Babovic, Gaetano Panese, Andrea Tinelli
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引用次数: 0

摘要

背景:盆底稳定性受各种生物力学、解剖学和生理学因素的影响。了解这些动态因素对于改善盆腔器官脱垂(POP)及相关疾病的治疗至关重要:分析影响盆底完整性的关键因素,并探讨非手术和手术干预措施,以提高稳定性和治疗效果:方法:本综述通过生物力学研究评估子宫骶骨韧带在骨盆支撑中的作用,同时探讨传统和新兴治疗方法的潜力,包括补充维生素 C 等非手术干预措施:- 结果:子宫骶骨韧带具有超强的强度和刚度,对骨盆器官的结构支撑至关重要。- 维生素 C 补充剂等非手术干预措施在改善韧带完整性和预防盆底疾病方面显示出潜力。- 新出现的手术技术,包括基于肌腱的手术和可注射纤维水凝胶复合材料,有望改善盆腔器官脱垂患者的治疗效果。- 肌肉力量和神经缺陷等其他因素增加了盆底生物力学的复杂性,表明需要采取多方面的治疗方法:这项分析通过整合生物力学、生理学和解剖学观点,为理解和管理盆底稳定性提供了一个全面的框架。研究结果凸显了个性化治疗策略的潜力,可改善盆底疾病患者的治疗效果。
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Fortifying the foundation: assessing the role of uterine ligament integrity in uterine prolapse and beyond

Background

Pelvic floor stability is influenced by various biomechanical, anatomical, and physiological factors. Understanding these dynamics is crucial for improving the treatment of pelvic organ prolapse (POP) and related conditions.

Objective

To analyze the key factors affecting pelvic floor integrity and explore both non-surgical and surgical interventions to enhance stability and treatment outcomes.

Methods

This review draws from biomechanical research to assess the role of the uterosacral ligament in pelvic support, while also examining the potential of both traditional and emerging therapeutic approaches, including non-surgical interventions like vitamin C supplementation.

Results

- The uterosacral ligament demonstrates superior strength and stiffness, making it essential for structural support of pelvic organs.

- Non-surgical interventions, such as vitamin C supplementation, show potential in improving ligament integrity and preventing pelvic floor disorders.

- Emerging surgical techniques, including tendon-based procedures and injectable fibrous hydrogel composites, offer promising improvements in outcomes for patients with pelvic organ prolapse.

- Additional factors such as muscle strength and neural deficiencies contribute to the complexity of pelvic floor biomechanics, indicating the need for multifaceted treatment approaches.

Conclusion

This analysis provides a comprehensive framework for understanding and managing pelvic floor stability by integrating biomechanical, physiological, and anatomical insights. The findings highlight the potential for personalized treatment strategies to improve patient outcomes in pelvic floor disorders.

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来源期刊
CiteScore
4.70
自引率
15.40%
发文量
493
审稿时长
1 months
期刊介绍: Founded in 1870 as "Archiv für Gynaekologie", Archives of Gynecology and Obstetrics has a long and outstanding tradition. Since 1922 the journal has been the Organ of the Deutsche Gesellschaft für Gynäkologie und Geburtshilfe. "The Archives of Gynecology and Obstetrics" is circulated in over 40 countries world wide and is indexed in "PubMed/Medline" and "Science Citation Index Expanded/Journal Citation Report". The journal publishes invited and submitted reviews; peer-reviewed original articles about clinical topics and basic research as well as news and views and guidelines and position statements from all sub-specialties in gynecology and obstetrics.
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