L-PRF 对下第三磨牙手术疼痛和愈合效果的影响:随机分口试验。

IF 1.5 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Brazilian oral research Pub Date : 2024-09-13 eCollection Date: 2024-01-01 DOI:10.1590/1807-3107bor-2024.vol38.0089
Raissa Pinheiro Moraes, Fábio Wildson Gurgel Costa, Paulo Goberlânio de Barros Silva, Francisco Samuel Rodrigues Carvalho, Jéssica Emanuella Rocha Moura Paz, Gabriel Carvalho Matos, Marcela Lima Gurgel, Edson Luiz Cetira Filho, Eduardo Costa Studart Soares
{"title":"L-PRF 对下第三磨牙手术疼痛和愈合效果的影响:随机分口试验。","authors":"Raissa Pinheiro Moraes, Fábio Wildson Gurgel Costa, Paulo Goberlânio de Barros Silva, Francisco Samuel Rodrigues Carvalho, Jéssica Emanuella Rocha Moura Paz, Gabriel Carvalho Matos, Marcela Lima Gurgel, Edson Luiz Cetira Filho, Eduardo Costa Studart Soares","doi":"10.1590/1807-3107bor-2024.vol38.0089","DOIUrl":null,"url":null,"abstract":"<p><p>This study explored the effects of L-PRF on pain, soft tissue healing, periodontal condition, and post-extraction bone repair of mandibular third molars (3Ms). A randomized, prospective, triple-blind, split-mouth clinical trial was conducted with 34 volunteers. Eligible patients were randomly allocated into two treatments: G1 (without L-PRF), G2 (alveoli filled with L-PRF), in which the removal of bilateral 3Ms was performed at the same surgical time. Outcomes were assessed according to a visual analogue scale (pain), soft tissue scoring system (wound healing), periodontal probing of mandibular second molar. Bone repair was determined by volumetric analysis (ITK-SNAP software) and fractal analysis (ImageJ software). An intention-to-treat approach to Statistical analysis was used. L-PRF reduced pain in the 7-day postoperative follow-up (p = 0.019) and not only improved soft tissue healing after 1 month of follow-up (p = 0.021), but also probing depth (distal face) in 3 months postoperatively (p = 0.011). Significant alveolar reduction occurred in 3 months after surgery in both treatments (p < 0.05), however, this was more significant in G1 (p = 0.016). The fractal dimension showed no statistical differences. L-PRF improved postoperative clinical parameters of pain, soft tissue healing, and periodontal condition, suggesting that it has a beneficial effect on preserving the alveolar ridge and accelerating the initial repair process.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404852/pdf/","citationCount":"0","resultStr":"{\"title\":\"Impact of L-PRF on pain and healing outcomes in lower third molar surgery: a randomized split-mouth trial.\",\"authors\":\"Raissa Pinheiro Moraes, Fábio Wildson Gurgel Costa, Paulo Goberlânio de Barros Silva, Francisco Samuel Rodrigues Carvalho, Jéssica Emanuella Rocha Moura Paz, Gabriel Carvalho Matos, Marcela Lima Gurgel, Edson Luiz Cetira Filho, Eduardo Costa Studart Soares\",\"doi\":\"10.1590/1807-3107bor-2024.vol38.0089\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study explored the effects of L-PRF on pain, soft tissue healing, periodontal condition, and post-extraction bone repair of mandibular third molars (3Ms). A randomized, prospective, triple-blind, split-mouth clinical trial was conducted with 34 volunteers. Eligible patients were randomly allocated into two treatments: G1 (without L-PRF), G2 (alveoli filled with L-PRF), in which the removal of bilateral 3Ms was performed at the same surgical time. Outcomes were assessed according to a visual analogue scale (pain), soft tissue scoring system (wound healing), periodontal probing of mandibular second molar. Bone repair was determined by volumetric analysis (ITK-SNAP software) and fractal analysis (ImageJ software). An intention-to-treat approach to Statistical analysis was used. L-PRF reduced pain in the 7-day postoperative follow-up (p = 0.019) and not only improved soft tissue healing after 1 month of follow-up (p = 0.021), but also probing depth (distal face) in 3 months postoperatively (p = 0.011). Significant alveolar reduction occurred in 3 months after surgery in both treatments (p < 0.05), however, this was more significant in G1 (p = 0.016). The fractal dimension showed no statistical differences. L-PRF improved postoperative clinical parameters of pain, soft tissue healing, and periodontal condition, suggesting that it has a beneficial effect on preserving the alveolar ridge and accelerating the initial repair process.</p>\",\"PeriodicalId\":9240,\"journal\":{\"name\":\"Brazilian oral research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2024-09-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404852/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Brazilian oral research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1590/1807-3107bor-2024.vol38.0089\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brazilian oral research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0089","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0

摘要

本研究探讨了 L-PRF 对下颌第三磨牙(3Ms)疼痛、软组织愈合、牙周状况和拔牙后骨修复的影响。研究人员对 34 名志愿者进行了随机、前瞻性、三盲、分口临床试验。符合条件的患者被随机分配到两种治疗方法中:G1(不使用 L-PRF)和 G2(用 L-PRF 填充牙槽骨),其中双侧 3Ms 的切除在同一手术时间进行。疗效根据视觉模拟量表(疼痛)、软组织评分系统(伤口愈合)和下颌第二磨牙牙周探诊进行评估。骨修复情况通过体积分析(ITK-SNAP 软件)和分形分析(ImageJ 软件)确定。统计分析采用意向治疗法。L-PRF 降低了术后 7 天随访的疼痛(p = 0.019),不仅改善了术后 1 个月的软组织愈合(p = 0.021),还改善了术后 3 个月的探诊深度(远端面)(p = 0.011)。两种治疗方法在术后 3 个月都出现了明显的牙槽骨缩小(p < 0.05),但 G1 更为明显(p = 0.016)。骨折维度没有统计学差异。L-PRF 改善了术后疼痛、软组织愈合和牙周状况等临床参数,这表明它对保护牙槽嵴和加速初始修复过程具有有利影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Impact of L-PRF on pain and healing outcomes in lower third molar surgery: a randomized split-mouth trial.

This study explored the effects of L-PRF on pain, soft tissue healing, periodontal condition, and post-extraction bone repair of mandibular third molars (3Ms). A randomized, prospective, triple-blind, split-mouth clinical trial was conducted with 34 volunteers. Eligible patients were randomly allocated into two treatments: G1 (without L-PRF), G2 (alveoli filled with L-PRF), in which the removal of bilateral 3Ms was performed at the same surgical time. Outcomes were assessed according to a visual analogue scale (pain), soft tissue scoring system (wound healing), periodontal probing of mandibular second molar. Bone repair was determined by volumetric analysis (ITK-SNAP software) and fractal analysis (ImageJ software). An intention-to-treat approach to Statistical analysis was used. L-PRF reduced pain in the 7-day postoperative follow-up (p = 0.019) and not only improved soft tissue healing after 1 month of follow-up (p = 0.021), but also probing depth (distal face) in 3 months postoperatively (p = 0.011). Significant alveolar reduction occurred in 3 months after surgery in both treatments (p < 0.05), however, this was more significant in G1 (p = 0.016). The fractal dimension showed no statistical differences. L-PRF improved postoperative clinical parameters of pain, soft tissue healing, and periodontal condition, suggesting that it has a beneficial effect on preserving the alveolar ridge and accelerating the initial repair process.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
3.70
自引率
4.00%
发文量
107
审稿时长
12 weeks
期刊最新文献
Brazilian Oral Pathology and Oral Medicine: current state of the study of rare diseases. A novel low shrinkage dimethacrylate monomer as an alternative to BisGMA for adhesive and resin-based composite applications. A YOLO-V5 approach for the evaluation of normal fillings and overhanging fillings: an artificial intelligence study. Cross-cultural adaptation of the eHealth Literacy Scale for Brazilian adolescents. Influence of the digital file format on radiographic diagnostic in dentistry: a scoping review.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1