迷幻植物 Mimosa tenuiflora (Willd.) Poir.

IF 1.9 3区化学 Q3 CHEMISTRY, APPLIED Natural Product Research Pub Date : 2024-09-18 DOI:10.1080/14786419.2024.2405875

Jady Vitoria Barjud Pereira Ferreira, Ana Marcia de Freitas Pessoa, Rita de Cassia de Lima Sousa, Carlos Mario Freitas de Oliveira, Laryssa Gomes Eulálio, Renato Pinto de Sousa, Gerardo Magela Vieira Júnior, Victor de Jesus Silva Meireles, Daniel Dias Rufino Arcanjo, Maurício Pires de Moura do Amaral

{"title":"迷幻植物 Mimosa tenuiflora (Willd.) Poir.","authors":"Jady Vitoria Barjud Pereira Ferreira, Ana Marcia de Freitas Pessoa, Rita de Cassia de Lima Sousa, Carlos Mario Freitas de Oliveira, Laryssa Gomes Eulálio, Renato Pinto de Sousa, Gerardo Magela Vieira Júnior, Victor de Jesus Silva Meireles, Daniel Dias Rufino Arcanjo, Maurício Pires de Moura do Amaral","doi":"10.1080/14786419.2024.2405875","DOIUrl":null,"url":null,"abstract":"The present work investigated the anxiolytic effect of the alkaloid fraction (AF II) from the root bark of Mimosa tenuiflora. Female Swiss mice of 6 weeks old were used in this study. The animals were divided into three groups: 0.9% NaCl (vehicle group, s.c.), AF II (6 mg/kg, s.c.), and diazepam - DZP (5 mg/kg, s.c.). The light/dark box and elevated plus maze tests evaluated the animal anxiety. DMT was identified by the HPLC method. AF II showed significant anxiolytic effects in the two behavioural tests used.","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The anxiolytic-like effect of the alkaloid fraction of the psychedelic plant Mimosa tenuiflora (Willd.) Poir.\",\"authors\":\"Jady Vitoria Barjud Pereira Ferreira, Ana Marcia de Freitas Pessoa, Rita de Cassia de Lima Sousa, Carlos Mario Freitas de Oliveira, Laryssa Gomes Eulálio, Renato Pinto de Sousa, Gerardo Magela Vieira Júnior, Victor de Jesus Silva Meireles, Daniel Dias Rufino Arcanjo, Maurício Pires de Moura do Amaral\",\"doi\":\"10.1080/14786419.2024.2405875\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The present work investigated the anxiolytic effect of the alkaloid fraction (AF II) from the root bark of Mimosa tenuiflora. Female Swiss mice of 6 weeks old were used in this study. The animals were divided into three groups: 0.9% NaCl (vehicle group, s.c.), AF II (6 mg/kg, s.c.), and diazepam - DZP (5 mg/kg, s.c.). The light/dark box and elevated plus maze tests evaluated the animal anxiety. DMT was identified by the HPLC method. AF II showed significant anxiolytic effects in the two behavioural tests used.\",\"PeriodicalId\":18990,\"journal\":{\"name\":\"Natural Product Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-09-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Natural Product Research\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1080/14786419.2024.2405875\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Product Research","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/14786419.2024.2405875","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}

引用次数: 0

摘要

本研究调查了含羞草根皮生物碱成分（AF II）的抗焦虑作用。本研究使用了 6 周大的雌性瑞士小鼠。动物分为三组：0.9%氯化钠（载体组，静脉注射）、AF II（6 毫克/千克，静脉注射）和地西泮 - DZP（5 毫克/千克，静脉注射）。光/暗箱和高架迷宫测试评估了动物的焦虑程度。DMT通过高效液相色谱法进行鉴定。在使用的两种行为测试中，AF II 均显示出明显的抗焦虑作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

The anxiolytic-like effect of the alkaloid fraction of the psychedelic plant Mimosa tenuiflora (Willd.) Poir.

The present work investigated the anxiolytic effect of the alkaloid fraction (AF II) from the root bark of Mimosa tenuiflora. Female Swiss mice of 6 weeks old were used in this study. The animals were divided into three groups: 0.9% NaCl (vehicle group, s.c.), AF II (6 mg/kg, s.c.), and diazepam - DZP (5 mg/kg, s.c.). The light/dark box and elevated plus maze tests evaluated the animal anxiety. DMT was identified by the HPLC method. AF II showed significant anxiolytic effects in the two behavioural tests used.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Natural Product Research 化学-医药化学

CiteScore

5.10

自引率

9.10%

发文量

605

审稿时长

2.1 months

期刊介绍： The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.