[免疫介导的神经病变:病理生理学和管理]。

Y Y Tian, P P Yuan, X G Wang
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引用次数: 0

摘要

免疫介导的神经病(IMN)是一组由于免疫系统失调而影响周围神经系统的异质性疾病。它主要包括格林-巴利综合征、慢性炎症性脱髓鞘多发性神经病、多灶性运动神经病等。这些疾病大多可以通过适当的免疫治疗得到临床改善,但仍有部分患者疗效不理想。因此,研究疾病发生、发展的病理生理学,可以揭示疾病的本质,为疾病的预防、诊断和治疗提供理论依据。本文以免疫学机制为重点,详细阐述了各种 IMN 的病理生理学机制,并简要介绍了各种 IMN 的诊断和治疗进展。
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[Immune-mediated neuropathies: pathophysiology and management].

Immune-mediated neuropathies (IMN) are a heterogenous group of disorders affecting the peripheral nervous system, due to dysregulation of the immune system. It mainly includes Guillain-Barre syndrome, chronic inflammatory demyelinating polyradiculoneuropathy, multifocal motor neuropathy and so on. Most of these diseases can be clinically improved by appropriate immunotherapy, but some patients still have unsatisfactory results. Therefore, studying the pathophysiology of the occurrence and development of diseases can reveal the nature of diseases and provide a theoretical basis for the prevention, diagnosis and treatment of diseases. In this paper, the pathophysiological mechanism of various IMNs is described in detail, with emphasis on immunological mechanism, and the progress of diagnosis and treatment of various IMNs is briefly introduced.

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来源期刊
中华预防医学杂志
中华预防医学杂志 Medicine-Medicine (all)
CiteScore
1.20
自引率
0.00%
发文量
12678
期刊介绍: Chinese Journal of Preventive Medicine (CJPM), the successor to Chinese Health Journal , was initiated on October 1, 1953. In 1960, it was amalgamated with the Chinese Medical Journal and the Journal of Medical History and Health Care , and thereafter, was renamed as People’s Care . On November 25, 1978, the publication was denominated as Chinese Journal of Preventive Medicine . The contents of CJPM deal with a wide range of disciplines and technologies including epidemiology, environmental health, nutrition and food hygiene, occupational health, hygiene for children and adolescents, radiological health, toxicology, biostatistics, social medicine, pathogenic and epidemiological research in malignant tumor, surveillance and immunization.
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