Xuwei He, Tianzheng Lou, Ning Zhang, Bin Zhu, Danyi Zeng, Hua Chen
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引用次数: 0
摘要
背景：由于败血症的高危性，急诊科急需一种简单的评估方法来评估败血症患者的炎症程度和预后，为诊断和治疗提供参考：由于败血症的高危险性，急诊科急需一种简单的评估方法来评估败血症患者的炎症程度和预后，为诊断和治疗提供参考：研究脓毒症患者中性粒细胞与淋巴细胞比值（NLR）结合血尿素氮与血清白蛋白比值（BAR）的预后价值：方法：选取2022年6月至2023年6月期间丽水市人民医院收治的377例败血症患者作为研究对象。根据预后分为生存组（255 例）和死亡组（82 例）。对两组患者的临床数据进行比较。采用多变量逻辑分析确定影响败血症预后的因素，并采用 ROC 曲线分析评估 NLR、BAR 及其组合的预测效果：与幸存者相比，非幸存者的 NLR 和 BAR 均较高，差异有统计学意义（P< 0.05）。调整混杂因素后发现，NLR（OR = 1.052）和 BAR（OR = 1.095）是脓毒症患者的独立预后因素（均 p< 0.05）。NLR结合BAR的AUC为0.798（95% CI 0.745-0.850，p< 0.05），高于单独NLR的AUC（0.776）和单独BAR的AUC（0.701）：结论：NLR 和 BAR 的组合对脓毒症患者的预后具有很高的预测价值。结论：NLR 和 BAR 的组合对脓毒症患者的预后具有很高的预测价值，其计算简单，特别适合急诊科使用。
Predicting survival in sepsis: The prognostic value of NLR and BAR ratios.
Background: Due to the high-risk nature of sepsis, emergency departments urgently need a simple evaluation method to assess the degree of inflammation and prognosis in sepsis patients, providing a reference for diagnosis and treatment.
Objective: To investigate the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) combined with the blood urea nitrogen-to-serum albumin ratio (BAR) in sepsis.
Methods: A total of 377 sepsis patients admitted to Lishui People's Hospital from June 2022 to June 2023 were selected as the study subjects. Based on their prognosis, they were divided into a survival group (255 cases) and a death group (82 cases). The clinical data of the two groups were compared. Multivariate logistic analysis was used to identify factors influencing sepsis prognosis, and ROC curve analysis was used to assess the predictive efficacy of NLR, BAR, and their combination.
Results: Compared with survivors, non-survivors had higher NLR and BAR, with statistically significant differences (p< 0.05). After adjusting for confounding factors, NLR (OR = 1.052) and BAR (OR = 1.095) were found to be independent prognostic factors for sepsis patients (both p< 0.05). The AUC of NLR combined with BAR was 0.798 (95% CI 0.745-0.850, p< 0.05), higher than the AUC of NLR alone (0.776) and BAR alone (0.701).
Conclusions: The combination of NLR and BAR has a high predictive value for the prognosis of sepsis patients. Its simple calculation makes it particularly suitable for use in emergency departments.
期刊介绍：
Technology and Health Care is intended to serve as a forum for the presentation of original articles and technical notes, observing rigorous scientific standards. Furthermore, upon invitation, reviews, tutorials, discussion papers and minisymposia are featured. The main focus of THC is related to the overlapping areas of engineering and medicine. The following types of contributions are considered:
1.Original articles: New concepts, procedures and devices associated with the use of technology in medical research and clinical practice are presented to a readership with a widespread background in engineering and/or medicine. In particular, the clinical benefit deriving from the application of engineering methods and devices in clinical medicine should be demonstrated. Typically, full length original contributions have a length of 4000 words, thereby taking duly into account figures and tables.
2.Technical Notes and Short Communications: Technical Notes relate to novel technical developments with relevance for clinical medicine. In Short Communications, clinical applications are shortly described. 3.Both Technical Notes and Short Communications typically have a length of 1500 words.
Reviews and Tutorials (upon invitation only): Tutorial and educational articles for persons with a primarily medical background on principles of engineering with particular significance for biomedical applications and vice versa are presented. The Editorial Board is responsible for the selection of topics.
4.Minisymposia (upon invitation only): Under the leadership of a Special Editor, controversial or important issues relating to health care are highlighted and discussed by various authors.
5.Letters to the Editors: Discussions or short statements (not indexed).
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